The Bloom Is Off the Bud: Santa Barbara County Taxes on Cannabis Hit New Low – Santa Barbara Independent

First-quarter county taxes on cannabis hit a new low this year, plummeting to $1 million. That’s down from $3.1 million the year prior and $4.2 million the year before that. This trend reflects the dramatic oversupply of cannabis — both legally and illegally grown — glutting the California market. 

According to a report submitted to the county supervisors on Tuesday, there are now 79 cannabis operations doing business in Santa Barbara County. Of those, 39 reported gross receipts, 16 reported no gross receipts, and 21 simply did not report.

Enforcement activity is down as well. During the first quarter, four actions were initiated — as opposed to eight the same time the previous year, with 300 plants confiscated as opposed to 3,250 the year before. During the first quarter, law enforcement seized $77,500 worth of dried cannabis; in the first quarter the prior year, it was $1.8 million worth. This also reflects the drop in value for cannabis.


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Minnesota’s medical cannabis program adds qualifying conditions: IBS and OCD – MPR News

Minnesota health officials are expanding the list of conditions that qualify for the state’s medical cannabis program.

The Minnesota Department of Health announced Wednesday that starting next August, people with irritable bowel syndrome and obsessive-compulsive disorder can receive medical cannabis — with certification from a health-care provider.

“We are adding the new qualifying conditions to allow patients more therapy options for conditions that can be debilitating,” Health Commissioner Jan Malcolm said in a news release.

In its announcement Wednesday, the health department said “research has shown that people who suffer from these conditions can see benefits from using medical cannabis to treat their symptoms.”

Certified patients with those conditions can start enrolling in the medical cannabis program on July 1, 2023 and start receiving medical cannabis on Aug. 1.

The additions announced Wednesday come after petitions to add the conditions went through a public comment period and passed a review panel. They’ll bring the list of approved qualifying conditions to 19 — up from nine when Minnesota’s medical cannabis program started in 2015.

The Health Department rejected two other petitions this year to add gastroparesis, or delayed gastric emptying, and opioid use disorder to the list.

State health officials said research has shown that cannabis can make gastroparesis worse. They also said they “heard from medical and mental health providers who recommended against approving opioid use disorder as a qualifying medical condition due to lack of evidence for its effectiveness and the availability of FDA-approved medications for treatment.”

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Minnesota expands medical cannabis access, adds two qualifying conditions – Star Tribune

Minnesotans with obsessive-compulsive disorder or irritable bowel syndrome will be able to manage their conditions with medical cannabis starting in August.

The expansion of Minnesota’s medical cannabis program, announced Wednesday, means 21 conditions will qualify for enrollment next year. Patients self-medicating for other conditions gained access this year in Minnesota to recreational gummies and other products containing THC — the psychoactive ingredient in marijuana — but the medical program remains tightly controlled.

„We are adding the new qualifying conditions to allow patients more therapy options for conditions that can be debilitating,” said Jan Malcolm, commissioner of the Minnesota Department of Health, in a written statement.

Participation in the program hasn’t slowed, despite this summer’s legislative decision to expand recreational THC options.

More than 39,000 Minnesotans are actively enrolled, which is up from 29,000 in 2021. Almost all participants qualified because of intractable or chronic pain, and about a third reported post-traumatic stress disorder. Muscle spasms, cancer and sleep apnea also were commonly reported as qualifying conditions.

Gastroparesis and opioid use disorder were not added to the list of qualifying conditions, with mental health providers advising against the latter as an option for people with addictions or dependencies to pain pills or illicit drugs. In public comments, one provider cited a study in which opioid-overdose deaths increased 23% in states allowing medical cannabis use.

The decision came in the face of a growing opioid overdose problem, and despite commenters stating that illicit or recreational cannabis had already helped them.

„After having gone (through) 9 years of painkiller use under medical prescription for pain, I know that the use of cannabis would help ease the withdrawal side of it,” said one commenter, only identified publicly by the initials TB. „I only use cannabis now.”

The new qualifying conditions offer a modest expansion — with an estimated 10% of adults having irritable bowel syndrome and 1% meeting the diagnostic criteria for OCD.

„My daily life consists of constant fear and stress,” said a man with OCD, who was identified by the initials RH and described himself as a working professional with a wife and two daughters. „Practically the only time I am free of the symptoms is when I am sleeping. Otherwise, for about 18 hours a day, I am constantly working to overcome the symptoms that I deal with day to day. It is exhausting.”

A state medical brief highlighted research supporting management of OCD with cannabis, but also noted opposition by Minneapolis-based Allina Health and some studies showing increased risk of addiction. A similar brief also highlighted the limited medication and treatment alternatives for IBS, indicating that medical cannabis could serve an unmet need.

Minnesota is among 38 states permitting medical cannabis, despite federal laws regulating marijuana as a drug with a high potential for abuse and prohibiting prescriptions by doctors.

From demand for cheaper products to FDA, CBD brands face difficult road – Natural Products INSIDER

Recent earnings results from the likes of CV Sciences Inc. and Charlotte’s Web Holdings Inc. highlight a grim reality: The CBD gold rush is clearly in the rearview mirror.

Growth in the CBD industry “has flattened out considerably since the pandemic hit,” said Bethany Gomez, managing director at Brightfield Group, a CBD and cannabis market intelligence firm.

“There was a dramatic increase in adoption in 2019 when CBD first went mainstream and the market grew by 560%,” she said in a Nov. 21 email to Natural Products Insider, “but since that time we have seen much more flat market performance.”

Several reasons account for the shift. The first comes down to price compression. Most brands have slashed prices by 20% to 40% in the last two years, and continue to offer significant discounts, Gomez said.

At the same time, price-conscious consumers have turned to less-expensive CBD products such as gummies, just as Charlotte’s Web has noted.

“American consumers are settling into their daily usage patterns, but looking to save money on their spend,” Gomez said. “This has made it difficult for companies to drive value growth, even if they are protecting margins.”

Meanwhile, when Covid-19 and all the subsequent shutdowns hit, most CBD brands “pivoted heavily” to e-commerce, Gomez noted. Those sales “soared” in the U.S. until the fourth quarter of 2021, she said.

Then, throughout 2022, e-commerce rates “absolutely plummeted.” They dropped from 40% to 19% as of the third quarter of 2022.

“For brands that were heavily focused on e-commerce, this shift has crushed them,” Gomez said. “Many consumers are increasingly going back out into the world and shifting their spend to local independent retailers.”

Other challenges facing the CBD sector are inflation and supply chain disruptions, as highlighted in recent quarterly results. 

„Our product costs have been impacted by inflation during the nine months ended September 30, 2022,” CV Sciences said in its quarterly report filed this month with the Securities and Exchange Commission. „Recent trends towards rising inflation may continue to adversely impact our business and corresponding financial position and cash flow.”

Regulatory headwinds 

Finally, there’s still no CBD guidance from the FDA, despite the September appointment of a cannabis policy chief. That means retailers remain limited in the brands they can sell, Gomez said.

Exacerbating the challenges facing brands, FDA continues to hold firm to its view that CBD cannot be lawfully added to conventional food or marketed in dietary supplements.

And on Nov. 21, in a constituent update announcing a batch of five FDA warning letters, the agency raised safety concerns—yet again—about CBD-containing foods.

Among the issues FDA highlighted in the constituent update:

– Consumers may confuse CBD-containing products for traditional foods or beverages.

– The agency is particularly concerned about such CBD-containing foods as cookies, gummies and hard candies because they may appeal to children.

– Use of CBD, especially long-term use, raises safety concerns, with scientific studies showing potential harm to the male reproductive system and interactions with certain medications.

– And in an online conversation, FDA officials Douglas Stearn and Kristi Muldoon-Jacobs also said it’s uncertain whether consumption of CBD could negatively affect fertility.

– Stearn and Muldoon-Jacobs also noted studies indicate CBD may increase and/or extend the effects of caffeine, which could be problematic for people sensitive to caffeine.

“We want to be clear that the data on CBD point to real risks that need to be considered,” Stearn and Muldoon-Jacobs said. “Risks include liver injury, harm to the male reproductive system and side effects, such as changes in alertness and other symptoms. In addition, drug interactions—taking CBD with other medications—may increase or decrease the effects of other medications, which may lead to more side effects from, or decreased effectiveness of, the other medications.”

FDA’s concerns are likely to contribute to prolonging the business challenges facing CBD brands, who may be counting on the upcoming 118th Congress to create a lawful pathway to market for ingestible products.

“We are not expecting significant movement at the regulatory level before the 2023 Farm Bill,” Gomez said, “though predicting movement on the regulatory environment is an imperfect science.”

Alpha Therapeutics’ Non-THC Broad Spectrum CBD Products Are Helping Americans Sleep, Heal, And Relax – Digital Journal

Alpha Therapeutics is creating powerful and effective CBD & CBG products to help millions of Americans fight the challenges of routine life such as body pain, insomnia, and stress.

The products from Alpha Therapeutics are made from organically farmed hemp and are GMO-free, gluten-free, and completely vegan. Since the company makes use of Broad-Spectrum CBD with no presence of THC, no medical marijuana prescription is needed to buy or use them. Alpha Therapeutics also values product quality and subjects its manufacturing output to periodic rigorous testing from the best laboratories in the country. Moreover, all of the products from Alpha Therapeutics are also wholly manufactured and use raw materials sourced in the USA, in Scottsdale, Arizona. Alpha Therapeutics is very confident in the quality of CBD products that it puts out and thus offers a 100% money-back guarantee on all purchases with free shipping anywhere within the USA.

Alpha Therapeutics

The lineup of products from the company made using CBD formulated by doctors includes CBD oil products such as the Extra Strength Oil and the Regular Strength Oil, topicals such as the Healing Balm and the Pain Stick, and Calm Sleep, a plant-based sedative. Alpha Therapeutics also makes available two product bundles – The Extra Strength CBD and Pain Stick bundle and the Extra Strength CBD and Healing Balm bundle.

The company’s CBD oil products help customers with headaches, body pain, and stress relief without the harmful side effects of traditional allopathic medications. They calm the body’s nerve receptors and reduce inflammation. The topicals from Alpha Therapeutics are designed to provide localized pain relief for aging or tired joints and muscles. The topicals get absorbed quickly through the skin providing fast relief that can help customers relax after a long day. Finally, its sedative formulation helps those suffering from sleep issues fall into a deep sleep and wake up feeling refreshed.

Alpha Therapeutics was established by Geoff Dada, a former marathon runner who needed a natural way for his body to recover after the stress of a grueling run. On the company’s website, he writes about his inspiration to investigate CBD as a solution by saying, “I loved the idea of CBD, but was disappointed by the results of the leading brands. Curious about the quality, I sent several of the leading brands to independent labs to see if their products had the ingredients they advertised. I was shocked to find some products only had a fraction of the CBD stated on their label. So, I began manufacturing CBD using medical quality processes. The results were amazing!”

Many of the customers who enjoy Alpha Therapeutics’ products agree with Geoff about the results. On the product listing for Calm Sleep, Alpha Therapeutics’ CBD oil for sleep, one reviewer says, “I used to use melatonin every night, but I would still wake up in the middle of the night and couldn’t easily fall back to sleep. This product has helped me fall back to sleep more easily and get a more restful sleep. Highly recommend this product!”

One reviewer heaps a ton of praise on the company’s Extra Strength CBD Oil by saying, “I have suffered from migraines for years. They are so bad that I have to lie down and miss out on time with my grandkids. Alpha CBD has allowed me to get my life back again!” Another reviewer talks about the efficacy of the Healing Balm by saying, “I have tried multiple CBD products that promised the moon but delivered nothing. This one promised to stop my hand from hurting. It did just that.”

A customer, who is also an athlete, recommends one of Alpha Therapeutics’ bundles by saying, “As an IFBB professional bodybuilder, I am careful about what I put in and on my body. I tried several brands of CBD before a client recommended Alpha CBD. This by far works the best. After years of surgeries and injuries, I can finally work out as if I am injury free!”

Readers can contact Alpha Therapeutics at [email protected] for inquiries.

###

For more information about Alpha Therapeutics LLC, contact the company here:

Alpha Therapeutics LLC
Geoff Dada
(833) 257-4279
[email protected]
10599 N Tatum
Suite F-156
Paradise Valley, AZ 85253

BelCosta Labs and U.S. Cannalytics Merge in Key East Coast Cannabis Markets – Yahoo Finance

BelCosta Labs

BelCosta Labs

Leading Cannabis Testing Labs From East and West Coast Markets Unify Brands as BelCosta Labs

LONG BEACH, Calif., Nov. 30, 2022 (GLOBE NEWSWIRE) — BelCosta Labs, a leading California third-party cannabis testing lab, today announced the company is expanding its operations beyond California. BelCosta is combining businesses with independent testing labs US Cannalytics (“USC”) and Pinnacle CT Labs (“PCT”). USC currently services Florida, New Jersey, and Pennsylvania, and PCT services Maryland. All laboratories will be rebranded and operate as BelCosta Labs.

The merger combines over ten years of cannabis-specific, analytical testing expertise from five different state markets to create a national laboratory group rooted in quality, transparency, and innovation. The new lab group is positioned to lead the evolution of the cannabis testing industry with best-in-class methodologies providing operators, patients, and consumers alike with detailed and accurate data to more effectively understand the cannabis experience.

We are thrilled to be expanding our business out of state for the first time since starting BelCosta in 2017,” said Myron Ronay, CEO of BelCosta Labs. “As one of the oldest testing labs in a mature market like California, we are eager to join forces with the U.S. Cannalytics team to provide cannabis producers across the country with high-quality testing services and insight.”

Founded in 2018, USC and PCT are a multi-state group of independent testing laboratories servicing medical and recreational cannabis and hemp/CBD markets. As one of the largest cannabis testing organizations on the East Coast with over seventy-five years of combined management experience across medical, pharmaceutical, and other professional fields, USC and PCT have emerged as leaders in the East Coast markets.

PCT is dedicated to ensuring a safe supply for medical cannabis patients in Maryland. PCT’s scientific team includes professionals with over 30 years of combined experience in their respective fields.

„We are excited to join BelCosta Labs and to work collaboratively with a great team to advance the cannabis testing industry,” said Karrissa Miller, Director of Client Services for USC and PCT. “USC and PCT pride ourselves on our highly skilled team’s vast experience and knowledge; joining BelCosta enhances our ability to exceed minimum regulatory and quality requirements for our current and future customer base.”

BelCosta Labs aims to use the latest analytic methods, customized technology and its staff of nationally renowned experts to provide top-quality compliance testing services for the cannabis industry.

About BelCosta Labs
BelCosta Labs is leading the evolution of cannabis lab testing through agricultural science, education, and technology. Combining analytic methods, customized technology, and years of expertise in the cannabis industry to provide the highest quality testing lab services for compliance. BelCosta Labs is a member of the American Council of Independent Laboratories (ACIL) Cannabis Working Group, ISO-accredited by the American Association for Laboratory Accreditation (A2LA), and Patient Focus Certified by Americans for Safe Access (ASA). Our staff comprises nationally renowned agricultural science experts, who have set the standard for accurate testing methods and are committed to providing the best testing lab services and pushing the boundaries of agricultural science and research.

About US Cannalytics and Pinnacle CT Labs
US Cannalytics, LLC and Pinnacle CT Labs are a multi-state group of independent testing laboratories servicing medical marijuana/medical cannabis and hemp/CBD markets in MD, PA, FL and NJ. Currently, one of the largest privately owned independent cannabis testing organizations on the East Coast, US Cannalytics and Pinnacle CT Labs provide world-class testing and services to our partners. With over seventy-five years of combined management experience across medical, pharmaceutical, and other professional fields, US Cannalytics and Pinnacle CT Labs leverages their vast experience and knowledge to exceed minimum regulatory, technical, and quality requirements.

Our core principles revolve around consistently producing high-quality results, using robust methods and processes, and nurturing genuine relationships within the cannabis industry and regulatory bodies. We are proud to provide the superior feedback necessary to produce market-leading products and ensure patient and consumer transparency and safety within the marketplace.

Subject to Regulatory Approval. The obligations of the parties hereunder are subject to all required regulatory approvals of each state regulatory body.

MEDIA CONTACT:
Trevor Maniscalo
NisonCo PR
trevor@NisonCo.com
(630) 841-1017

PureTech Announces New Therapeutic Candidate LYT-310, An Oral CBD Prodrug – PureTech Health (NASDAQ:PRTC) – Benzinga

PureTech Health plc PRTC PRTC announced the nomination of a new therapeutic candidate, LYT-310, which is an oral CBD prodrug and the second therapeutic candidate developed from PureTech’s Glyph platform to be advanced toward the clinic. Clinical studies of LYT-310 are expected to begin in Q4 of 2023.

A CBD-based product has received regulatory approval in the United States and Europe to treat seizures resulting from certain rare conditions, but it requires a large volume of a sesame oil-based formulation, which limits its use in broader indications and age groups. PureTech’s LYT-310 is designed to greatly expand the therapeutic application and potential of CBD by:

  • enabling oral administration in a capsule;

  • expanding the use of CBD into a broad range of therapeutic areas and patient populations where higher doses are required to achieve a therapeutic effect;

  • potentially improving safety and reducing gastrointestinal tract side effects that are associated with the currently approved CBD-based treatment by reducing GI and liver exposure;

  • allowing for a readily scalable, consistent product in a cost-effective manner.

“The nomination of LYT-310 is an exciting expansion of PureTech’s Glyph technology,” stated Daniel Bonner, Ph.D., vice president at PureTech Health. “The data generated to date with LYT-310 further demonstrate our ability to apply the Glyph technology to an array of molecules to enable or greatly enhance oral bioavailability. This approach allows us to unlock the therapeutic potential of a range of molecules with validated efficacy whose development has been limited by first pass metabolism by the liver.”

In multiple preclinical models, including large animal and non-human primate, LYT-310 has demonstrated a three to fourfold increase in oral exposure vs. unmodified CBD in a fasted state. This has the potential to translate into improved safety and reduced side effects. Lymphatic transport has also been confirmed in preclinical models, with up to 30% of LYT-310 entering the lymphatics, compared to 5% for unmodified CBD – which further supports the novel Glyph mechanism of enhancing bioavailability.

The first candidate from the Glyph technology platform, LYT-300, is currently being evaluated in a multi-part phase 1 trial designed to demonstrate oral bioavailability, evaluate safety and tolerability across a range of doses, and to inform dose selection moving forward. The first objective was achieved earlier this year, and LYT-300 demonstrated oral bioavailability of allopregnanolone approximately ninefold greater than that of orally administered allopregnanolone, based on previously published data. The phase 1 clinical trial is expected to be completed by the end of 2022, and – based on the data – a phase 1b/2a clinical trial is planned to initiate in 2023.

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Graphic: Courtesy of Business Wire

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