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CBD reduces anxiety symptoms by up to 50% in young people – Medical News Today

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Researchers believe cannabidiol (CBD) could be an effective treatment for anxiety in some people. Merve Betül Karakus/EyeEm/Getty Images
  • Many young people have anxiety, which interferes with their ability to go about their daily lives.
  • Treatment for anxiety includes a variety of approaches, including cognitive behavioral therapy and sometimes medication use.
  • A recent pilot study found that cannabidiol (CBD)—the non-mind-altering part of cannabis— almost halved chronic anxiety symptoms in young people.
  • The study adds to existing research suggesting that CBD could be a successful treatment option for young people with treatment-resistant anxiety.

Everyone experiences some level of anxiety. However, experiencing too much anxiety can impair people’s ability to cope and work through challenges in day-to-day life. Treatment for anxiety can include the use of certain medications and counseling or cognitive behavioral therapy.

A recent study published in The Journal of Clinical Psychiatry found that cannabidiol might be a safe anxiety treatment for young people who have not responded well to other types of therapy.

Anxiety is one of the most common mental illnesses.

The National Institute of Mental Health notes, “For people with an anxiety disorder, the anxiety does not go away and can get worse over time. The symptoms can interfere with daily activities such as job performance, schoolwork, and relationships.”

Dr. Lewis Jassey, medical director at Leafwell, who was not involved in the study, elaborated on the impact of anxiety.

“Anxiety can lead to both mental and physical problems. Anxiety is often comorbid with depression, with more than 70% of patients with lifetime generalized anxiety disorder (GAD) also having major depressive disorder (MDD). [F]urthermore, being under constant stress and anxiety can lead to a dampened immune system, which can increase the likelihood of suffering from an infection,” he told Medical News Today.

“Panic attacks, irritability, headaches, muscle aches, increased heart rate, heart palpitations, increased blood pressure, breathing problems, upset stomach, insomnia, and chronic fatigue are all common effects of anxiety.”
— Dr. Lewis Jassey

Treatment for anxiety will often involve approaching the problem from multiple angles.

For example, a doctor might prescribe certain medications to help improve symptoms. Treatment may also involve psychotherapy, which involves evaluating and changing thinking patterns to help reduce anxiety. People with anxiety may also benefit from support groups or stress management techniques.

Sometimes, people do not respond well to these treatments and still experience high anxiety levels. Hence, experts are examining additional and alternative treatment methods that may be effective.

Cannabidiol (CBD) is the portion of cannabis that doesn’t have mind-altering effects. The study was an open-label trial that included 31 people between the ages of 12 and 25. All participants met the criteria for a DSM-5 anxiety disorder and had not experienced an improvement in anxiety from previous interventions.

For twelve weeks, participants received the add-on treatment of CBD, with doses increased up to 800 mg/d as needed.

Overall, participants experienced over 40% reduction in anxiety severity based on the Overall Anxiety Severity and Impairment Scale (OASIS). Participants also experienced an improvement in social and occupational functioning and a decrease in depressive symptoms.

The study’s results indicate a potential treatment option for anxiety in people who have not responded well to other treatment types.

While discussing the study’s findings, study author Professor Paul Amminger explained:

“There’s a lot of hope that a novel compound which is benign, like cannabidiol, could ease mental health problems. I think that the most exciting finding of the study was that the anxiety severity, which was on average severe to very severe, dropped by 50% at the end of the trial.”

Study author Emily Li further noted:

“A lot of people reported [a] decrease in tension. They have reported just feeling generally more relaxed. They reported[ fewer] panic symptoms. They also reported a feeling of calmness.”

“Others have reported that because of the effect of the CBD, they no longer needed to, perhaps, use illicit substances to self-medicate,” she added,

This study opens the door for further research into cannabidiol as a treatment option for individuals with severe anxiety.

However, the study had a limited sample size and lasted only twelve weeks. This indicates the need for studies involving more participants and a longer follow-up time.

Participants also reported some side effects from using CBD, including low mood, fatigue, cold chills, and hot flashes, yet, there were no major adverse events. Further long-term research could also monitor participants for any additional side effects of CBD use.

A placebo effect?

The authors also noted that a placebo effect was possible, so further research should include a randomized control trial.

“Our trial was open-label and uncontrolled therefore casual inferences about the efficacy of cannabidiol (CBD) relative to other influences (e.g., placebo effect) cannot be made with certainty,” said Prof. Amminger.

However, he also noted the data that supported it wasn’t a placebo effect:

“However, given that the patients included in this trial were some of the most severe treatment-resistant with significant functional impairment who had multiple failed treatment attempts prior their participation in our trial, the observed reduction in anxiety severity suggests that cannabidiol has clinically meaningful anxiolytic effects. Nevertheless, randomized controlled clinical trials are needed to confirm the efficacy and longer-term safety of CBD.”

As research continues, researchers will hopefully discover more effective anxiety treatments. Dr. Jassey was optimistic about the findings of this current study and believes pursuing cannabidiol as a treatment option holds promise.

“This study shows that young people reduced anxiety by up to 50%, including feeling more relaxed and less consuming illicit substances for self-medication,” he said.

“Cannabidiol (CBD) treatment holds plenty of promise. For 50% of people, antidepressant medications do not work, on top of taking several weeks of regular intake to find out if they actually work or not. Young people, in particular, may benefit, as CBD is far more tolerable and less impactful on the body than antidepressants, especially the harsher ones prescribed for treatment-resistant anxiety.”
— Dr. Lewis Jassey

New Mexico Reviews Past Cannabis-Related Charges for Expungement – Cannabis Business Times

Americans owe an estimated $195 billion in medical debt, according to RIP Medical Debt, and that number only continues to grow by the day. Medical debt, or the fear of exorbitant bills, prevents many people across the country from getting the medical treatment they need.

“Medical debt is a huge burden on Americans,” says Daniel Lempert, the VP of Communications at RIP Medical Debt , a non-profit organization that helps alleviate medical debt for patients with outstanding medical debt.  “People are choosing to pay rent or put food on the table. There’s also a mental health anguish that comes along with it. The stress of all that can actually make people sicker. We are also seeing people avoid going to the doctor, especially if they already owe medical debt, even though they might need to go back. People will seriously reconsider getting the healthcare they need for fear of having more debt.”

To help medical patients in California with an overwhelming amount of medical debt, RIP Medical Debt has partnered with cannabis companies Wellgreens and Pacific Stone. Wellgreens is a San Diego based cannabis dispensary that aims to de-stigmatize cannabis use. Pacific Stone is a cannabis cultivator company that single sources their flower. The partnership’s goal is to abolish $3 million of medical debt for people in California. “When I think of cannabis having started on the medical side, this is a really interesting way to go full circle and tie it all together with this collaboration,” says Skip Motsenbocker, CEO  of Pacific Stone.

RELATED: Pacific Stone Partners with RIP Medical Debt to Alleviate Medical Debt

This partnership between the brands evolved organically, Mostenbocker says. Wellgreens was Pacific Stone’s number one supplier in San Diego leading to the store takeover, where RIP Medical Debt and Pacific Stone advertise their campaign in the Wellgreens stores. RIP Medical debt fit right in when Wellgreens and Pacific Stone decided they wanted to collaborate with a nonprofit to help their communities. “It’s a great way to say to the rest of the world ‘hey, cannabis isn’t a bad thing,’” says Motsenbocker. “We are out trying to do good things …. Everybody should have some sort of an affiliation with an organization that figures out unique ways to give back to the community.”

RIP Medical Debt buys medical debt at a discount in bulk, giving the organization the ability to translate every dollar donated to relieving $100 of medical debt, according to a press release about the partnership.

 “What’s really amazing about it is the 100x multiplier,” Motsenbocker says. “For instance, we’ve kicked off the initial program to raise $30,000, but in that essence that $30,000 eradicates $3 million in medical debt.”

RIP Medical Debt buys patients’ debt in bulk from hospitals, connecting with people who need financial support anonymously. The hospital or partnering organization then contacts the patients  telling them their medical debt has been paid off. “We are a HIPPA-compliant organization,”  Lempert says. “So, we have proprietary software we use to identify, either with a hospital or a partner with the secondary debt market, we’ll scan the bulk debt they possess and scan the ones that meet our criteria. Households that earn less than four times  the poverty level are the most in need.”

So far, RIP Medical Debt has erased more than $6 billion in medical debt across the country. According to their 2021–year-end report, “In 2021 RIP Medical Debt abolished $2.7 billion of medical debt for 1.3 million people.” RIP Medical Debt hopes to grow this number even more with their most recent partnership within the cannabis industry.

With cannabis still being criminalized  and stigmatized, Luis Ituarte, Director of Licensing for Wellgreens says this partnership brings light to what the cannabis industry is about. “Cannabis still gets such a bad rep,” says Ituarte. “Not a lot of nonprofits open their doors for us. We aren’t the only dispensary that wants to give back to the community. We all want to give back. There are many philanthropists in the cannabis community. It’s helpful to have organizations like [RIP Medical Debt] who are spearheading the movement.”

Rapper Moneybagg Yo On Cannabis, NFTs: ‘Everybody Needs Discipline, But You Also Have To Smoke Weed’ – Forbes

“I just fell in love with weed, the texture. Now I like to learn more about it and when to use it, how to feel relaxed when smoking it,” says rapper DeMario DeWayne White Jr., better known as Moneybagg Yo. Despite this renewed interest in cannabis, DeMario has been consuming marijuana since he was a teenager – even though he obviously recognizes the perils of using pot at a young age.

“Before I perform or before I do interviews, I don’t smoke weed, I like to stay focused. But when I record, it’s a must-have. So I feel like it just is all-around,” he adds.

“I feel like you need to have discipline, everybody needs discipline. But I feel like you also have to smoke weed, bro; it’s a part of life. I feel like there aren’t a lot of dangers associated with smoking weed; it’s all about how you do it. For instance, I didn’t smoke before this interview, I don’t smoke before I do shows, I like to be fully focused on the work I do. I smoke when I’m in a studio and I want to think, I want to create or I want to relax. I know how to use cannabis.”

NFT Stands For New Found Trust

Moneybagg recently partnered with Trufflez Inc., a vertically integrated cannabis company that’s very focused on customer loyalty and user experiences, and droppLabs,a holistic Web3 solutions provider. Together, they launched the TrufflezNFT, a project that uses NFTs to register and fractionalize the intellectual property rights inherent to the trademarks and copyrights of new proprietary cannabis strains.

In layman’s terms, what this means is that people can partner with a fully licensed cannabis company through the purchase of a non-fungible token. In addition, the NFT carries a suite of additional benefits like discounts, access to exclusive products, profit sharing, private events and more.

MORE FROM FORBESRapper Vic Mensa Launches His Own Cannabis Brand: 'Before I Ever Sold A Rap, I Sold An Eighth’


The artist decided to jump into the cannabis NFT world after meeting Leo Hairapetian, CEO and co-founder of Trufflez. “We bonded tight,” the rapper says. “Leo was always telling me stuff that I didn’t know much about, so it just made it interesting.”

In fact, Moneybagg had partnered up with a couple more people prior to Trufflez. “I thought it was cool at the moment. But then, when I got with Trufflez, Leo and all the staff, I felt at home, I felt like, ‘this is where I belong.’ It just didn’t feel like anything else. I fell in love with the whole thing.”

And he adds: “Trufflez and Leo really introduced me into this world [NFTs]. Like, I really don’t fully understand it yet, but I know they do. They fully understand it, and I know they’re going to get me to the point… I listen, I learn quickly, so I feel like I can catch on to it quickly. Also, I just trust Leo, whatever he’s got going on, I’m bagging it 100% because I already know it’s going to speak. And I just feel like it can be a new way, a new world, for the digital world of NFTs.”

As Leo explains, Trufflez’s attention to detail has a lot to do with the rapper’s view of the brand. “Initially, when the brand started, our whole core fundamental concentration was to make sure that the public and whoever was smoking was extremely happy with whatever we had. And, we built on those building blocks by making sure that we take every opportunity within the industry to give back to the public.”

“That’s why the NFT project came so swiftly into place because we saw an opportunity to bring the NFT project for the general public to get involved and benefit from the company’s growth, get more involvement and feel like they’re part of something that’s vastly growing.”

Kyle Kneubuhl, CFO of Trufflez, further elaborates on the rationale behind the decision to launch an NFT: “There’s a lot of taboo still within the industry due to the federal government still has not legalized marijuana… That prohibits us in a lot of fashions from going public and issuing out stock, because we cannot go on the stock market.”

In Kneubuhl’s view, “The safer and more lucrative alternative route is more on the crypto and NFT, which serves the public in the same fashion, or more, on a Web3-based platform. So we don’t want to actually wait to provide these benefits to the public until the federal government passes the laws and legalizes it. We want to do it more exclusively now. And we feel that the Web3 and NFTs and cryptocurrency and Tokenomics are the future The digital world is coming swiftly and quickly, as you can imagine. And I think that is going to be the new base platform and the future.”

MORE FROM FORBESWhy Saint JHN Loves Weed Edibles: 'The Road Less Traveled Always Leads To Somewhere That Is Way More Sexy’

Nowadays, Moneybagg’s role in Trufflez is not at all minor. The musician is involved in a bunch of things, from marketing to strain selection and even breeding. In fact, the team recently co-developed a new strain called Truffle Bake, a cross between Purple Trufflez and While Trufflez. good

“Bagg is being a little modest in reference to his expertise in cannabis,” Leo interjects. “One thing that he obviously never speaks of is his immaculate palate for the taste of exotic cannabis, and that comes naturally for him. It’s been a seamless integration for us; it’s not that difficult because he knows good weed when he smokes it.”

But “good” weed is a very subjective term. So, what defines good weed for Moneybagg?

In true Goldilocks fashion, he responds, “The taste has to be there, this is where you begin. But you also can have weed that tastes good, but you don’t ‘levitate’ with it, it don’t put you where you need to be, high. So I feel like you need all in one package. It has to taste good, it has to hit right, it has to break down nicely… It can’t be too soft or too hard, it has to be in the middle.”

Legalize It Already

In Moneybagg’s view, cannabis should be legal in the U.S. Period.

“I think weed should be legal for a lot of reasons. Everybody don’t use it for the stuff they think people use it for. Some people really need it, to focus, go get they mind right, to calm them down… I’ve got a brother who’s hot-headed, but if he smokes, he’s thinking, he’s levelheaded, he’s cool,” he discloses.

MORE FROM FORBESThis Is (Probably) The Most Popular Cannabis Content Creator In The World: Meet Dope As Yola

But, doesn’t weed “fry” your brain? Doesn’t it make you a stereotypical “lazy stoner”?

For the artist, the answer is “no.”

“Man, get up, get you some money, stay focused. Know how to use cannabis, know when to do it; don’t let it throw you off,” he recommends. “Some people get high and totally distracted or lazy. But you just gotta get up and you just got to know how to use it, bro. You just got to stay motivated in the same process.”

As the conversation gets deeper, Moneybagg starts sharing some more personal stories. In the last few years, he’s had the privilege and honor of sharing a joint – or several, with two of his idols: Wiz Khalifa and Snoop Dogg.

“I went on tour with Wiz and he introduced me to his friends. We smoked together and he’s actually just a good OG, you know what I’m saying? So I’ll learn a lot from him, about cannabis, about all the different flavors. What he smokes, what he likes, is just a strong O.G. that makes you feel good, uplifted, but it’s also very exotic.”

Snoop also shared a cannabis-infused moment with Mr. Bagg. It was back at his studio, The Compound. “We smoked a few blunts, I gave him a couple of pounds of Trufflez weed and he loved it. He’s still calling right now like, ‘Nephew, I need some more of that fire.’”

Michigan’s Top Cannabis Regulator Leaves Position – Cannabis Business Times

After fearing signature shortfalls in two key congressional districts just two weeks ago, activists from Legal Missouri 2022 received certification from Secretary of State Jay Ashcroft on Aug. 9 for an adult-use cannabis ballot measure.

If all goes according to plan for the initiative’s proponents, Missouri will become the 20th state to legalize adult-use cannabis in the U.S. when voters go to the polls this November.

State officials certified 214,535 voter signatures—of roughly 400,000 submitted by Legal Missouri on May 8—from across Missouri’s eight congressional districts. That mark exceeded the required minimum of 184,720 valid signatures needed to appear on the ballot.

“Our statewide coalition of activists, business owners, medical marijuana patients and criminal justice reform advocates has worked tirelessly to reach this point and deserves all the credit,” Legal Missouri campaign manager John Payne said in a press release. “Our campaign volunteers collected 100,000 signatures, on top of paid signature collection. That outpouring of grassroots support among Missourians who want to legalize, tax and regulate cannabis made all the difference.”

The group’s victory on Tuesday came after early signs in the verification process indicated potential signature shortages on July 26. To qualify a petition for the ballot, an initiative effort must include valid signatures from 8% of voters in at least six of the eight congressional districts. Legal Missouri’s effort had only crossed the finish line in four districts at that time.

RELATED: Twice the Required Signatures Not Enough (Yet) For Missouri Cannabis Ballot Initiative

But Ashcroft announced Legal Missouri met that statutory requirement in issuing the sufficiency certificate on Aug. 9.

“I encourage Missourians to study and educate themselves on any ballot initiative,” Ashcroft said in a press release. “Initiative 2022-059 that voters will see on the November ballot is particularly lengthy and should be given careful consideration.”

The proposed constitutional amendment will be listed on the ballot as Amendment 3 and would allow Missourians ages 21 and older to possess, consume, purchase and cultivate cannabis.

The proposal would also allow individuals convicted of nonviolent cannabis-related offenses to petition to be released from incarceration and/or have their records automatically expunged.

If passed, the criminal justice reform aspect of the constitutional amendment would make Missouri the first state where voters took such a step, according to Legal Missouri. Current Missouri law requires those seeking to vacate their convictions to first petition the courts, an expensive and time-consuming process, according to the group.

The initiative’s automatic expungement provision will provide a clean slate to those whose past convictions become what the University of Missouri-Kansas City School of Law calls “the punishment that never ends.”

“Despite having fully paid their debt to society, they find that the impact of their record lingers, blocking educational, employment and housing opportunities,” the UMKC Law report concludes.

In addition, the ballot measure aims to establish a lottery to award licenses distributed equally to congressional districts. A new category of cannabis licenses would be reserved for small businesses, which, over time, would add a minimum of 144 licensed facilities to the existing 393 medical cannabis businesses in the state. Each of the state’s eight congressional districts would include at least six new retail licenses for adult-use cannabis under the new category.

Finally, the proposal would require a registration card for personal cultivation and impose a 6% tax on cannabis sales, among other provisions.

The 6% state sales tax would generate an estimated annual revenue of more than $40 million, according to a state auditor’s projection analysis. That money would cover the costs associated with implementing a state-licensed program as well as automatic expungement, with remaining funds allocated to veterans’ services, drug addictions treatment and Missouri’s public defender system.

Certification of the adult-use ballot initiative was delivered by the entire medical industry and activists, such as NORML and the NAACP, working together to push the signature drive across the finish line, Greenlight Dispensaries CEO John Mueller said in a statement to Cannabis Business Times.

A vertically integrated multistate operator, Greenlight has 15 retail operations in Missouri.

“In a tough COVID labor climate, it took the grassroots efforts of all parties to get the signatures needed to get this on the ballot,” Mueller said. “If approved by the Missouri voters in November, the constitution will extinguish the illicit market and regulate and tax an estimated $1 billion in cannabis in what many of the other MSOs formerly saw as ‘flyover country.’ Greenlight is well positioned to meet this consumer demand as cannabis regulation is spreading throughout the Midwest—with states like Missouri leading the way.”

A SurveyUSA poll released last month that included nearly 2,000 registered voters in the state, revealed that 62% of Missourians supported legalizing adult-use cannabis.

“Recent polling reveals that a majority of Missouri residents are ready and eager to end their state’s failed marijuana prohibition,” NORML Executive Director Erik Altieri said in a public statement Tuesday.

“That is because Missourians, like the overwhelming majority of all Americans, recognize that prohibition is a disastrous and draconian practice best cast into the waste bin of history,” Altieri said. “Voters in the Show Me State want a sensible policy of legalization and regulation, and that is why we expect that they will overwhelmingly vote ‘yes’ on this initiative this fall.”

The Legal Missouri initiative is supported by NORML, the ACLU of Missouri, Empower Missouri, Missouri Association of Criminal Defense Lawyers, the Reale Justice Network, the St. Louis City, St. Louis County and St. Charles County chapters of the NAACP, and others.

According to Legal Missouri, additional highlights of the petition include:

  • Allows local governments to assess local sales taxes of up to 3%.
  • Violent offenders and those whose offenses involved distribution to a minor or operating a motor vehicle while under the influence of cannabis would be ineligible for expungement.
  • Allows local communities to opt out of adult-use retail sales through a vote of the people.
  • Strengthen Missouri’s medical cannabis program. The petition extends the amount of time that medical cannabis patient and caregiver ID cards are valid from one to three years while keeping that cost low ($25). And the current $100 fee for Missourians who choose to grow medical cannabis at home will be reduced by half, with the expiration period also extended from one to three years.
  • Provides employment discrimination protection for medical patients, preventing them from being denied employment or being disciplined or fired for off-the-job medical cannabis use.
  • Seeks to broaden participation in the legal cannabis industry by small business owners and among historically disadvantaged populations, including those with limited capital, residents of high-poverty communities, service-disabled veterans and those previously convicted of non-violent cannabis offenses
  • Adds nurse practitioners to the category of health care professionals who can issue medical cannabis recommendations to patients.

2022’s Best Delta 8 Carts – Top-rated Vape Cartridges from Leadings THC Brands – Washington City Paper

As Descartes so eloquently said − I vape, therefore I am.

Or something like that…

But unfortunately for the famous philosopher − Delta 8 wasn’t legal back then.

This is why he had to get high on philosophy instead. (Tough life)

But fortunately for you, the Dark Cartages are now over.

(And hopefully, my bad jokes will soon follow)

So, to give you only the best Delta 8 carts to relax and fly…

Our team has spent weeks carefully analyzing all the important factors such as natural ingredients, strain variety, flavors, hemp quality, extraction method, manufacturing processes, lab tests, and more.

Ready for modern philosophy? Let’s go.

Best Delta 8 Cartridges – First Look

  1. Exhale – Best-rated brand (free shipping and 20% OFF*)
  2. Delta Extrax – Strong cartridges (15% discount with code Paradise15)
  3. BudPop – Legit Delta 8 carts with lab certification (25% OFF on recurring orders)
  4. Diamond CBD – Largest selection of flavors (all-year-round discounts)
  5. 3CHI – 51 (!) Delta 8 strains with 1,300+ positive reviews
  6. Moonwlkr – Smooth carts (regular promos and discounts)
  7. JustDelta8 – Cheap but potent Delta 8 THC vape carts
  8. Binoid – 15 strains of thoroughly tested vapes
  9. Boston Hemp – Transparent brand (generous discounts on bulk purchases)
  10. Secret Nature CBD – Artisanal approach to CBD products

1. Exhale Wellness – All-Round Best Delta 8 Cartridge Brand

Exhale, also known as Exhale Wellness, is a company that can mix top-tier THC products with the kind of convenient service that makes them #1 in the cannabis industry.

Not content with being featured in Forbes and the Los Angeles Times, the brand also has an impressive 4.4 rating on Trustpilot, where reviews are generally very harsh.

And when it comes to the meat of it − Exhale produces some of the best Delta 8 carts in terms of quality.

For one, they’re strong: each 1 ml contains 900 mg of Delta 8 THC, so they should help you relax.

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And if that weren’t enough…

Exhale Wellness also uses the best extraction method in the industry − CO2 extraction. It’s considered the safest and cleanest method, with the huge benefit of not leaving harmful substances.

Our favorite flavors from their Delta 8 offerings include

  • Gorilla Glue
  • Fruity Cereal
  • OG Kush

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Customer experience

When it comes to actual customers who have bought hemp-derived products like Delta 8 disposable vape pens and cartridges…

Most are very happy about the quality, saying these carts give them strong effects and that Exhale’s customer service is very helpful in case there’s a problem with your order.

As expected, many buyers also love Exhale’s free shipping and 30-day money-back guarantee.



  • No choice of potency

2. Delta Extrax – Strongest Delta 8 Cartridge

Delta Extrax might soon be the top dog in the vape cartridge industry because they offer more than just vape pens and cannabis strains to their customers; they provide some much-needed education as well.

Delta Extrax’s site accompanies each product category with a detailed guide to ensure their customers know exactly what they’re getting.

And when it comes to their top Delta 8 THC cartridges, customers can expect lab-tested products with no artificial additives to make sure you get a smooth vaping experience.

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Is the unprecedented 1 gram of full-spectrum hemp extract contained in each cart. With no exaggeration, this might be the strongest Delta 8 THC cart around.

Available in Indica, Sativa, or Hybrid strains, you’ll find a cart for every need, whether it’s to relax and watch a movie or to be in a better mood for socializing.

And to top it off…

You can get 15% OFF on all Delta Extrax’s products by using our coupon code Paradise15.

Their best sellers include:

  • Strawberry Cough
  • Cali Orange Kush
  • Grand Daddy Purp

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Customer Experience

Of the hundreds of reviews we’ve looked at, customers seem very happy with Delta Extrax’s customer support team.

The team is always ready to answer your questions about any specific Delta 8 THC cartridge so that you can make an informed decision.

But more importantly, most buyers say their carts provide a great high with none of the coughing that’s unfortunately common with cheaper brands.



  • Too intense compared to most established brands

3. BudPop – USA-made Vegan-friendly Delta 8 Vapes

Go with BudPop if you want THC products that have zero residual solvents and contain nothing but pure cannabis-derived terpenes.

Not only are their carts made in the USA with organic hemp and no artificial additives, but they also come with a QR code so that you can quickly access the lab reports.

I’d say this goes a long way in showing transparency.

When it comes to potency, BudPop’s carts offer a mellow experience with 800 mg of Delta 8 THC − this makes them perfect for beginners or sensitive users.

Unfortunately, BudPop’s focus on quality means their carts are only available in 2 options, with no choice between Indica and Sativa. Both options are Indica-dominant hybrids, which means they’re better for relaxing or helping you fall asleep.

Finally, BudPop uses natural flavors that are sweet and enjoyable, as well as natural terpenes for a more “real” taste.

With 1,000+ online customer reviews, BudPop may not be as established as Exhale Wellness (yet), but we think it’s slowly but surely making its place.

Some of their best sellers include:

  • Strawberry Gelato
  • Grape Runtz

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Customer Experience

When it comes to reviews from actual users, most say they like that the carts are smooth (not harsh) but they can still get “as high as a kite”.

As expected, most buyers also love the 20% discount on first orders and 25% discount on subscription plans − which many people use after getting their first batch and seeing the results.



  • THC products only available on the official site

4. Diamond CBD – Serious Discounts on Delta 8 Cartridge Brands

When you want Delta 8 THC vape carts at the best price, Diamond CBD immediately comes to mind.

Not only do they run frequent sales and discounts up to 40% off, but they also let you choose between dozens of popular brands like 10X, Chill Plus, Mellow Fellow, and more.

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But you don’t need to ask…

Because Diamond CBD goes a step further anyway: they make sure that all their products are GMO-free and federally legal.

And with so many brands to choose from, they obviously have one of the largest selections of Delta 8 cartridges online.

Not to mention they’re some of the strongest too.

For instance, 10X Pineapple Express carts contain a whopping 900 mg of D8 for every 1 ml of vaping juice − which makes them as strong as Exhale’s.

In other words, they should give you a high intense enough to make you feel good, but not too strong so that you’d have a bad trip.

Here are a few of our favorite flavors:

  • Pineapple Express
  • Sour Diesel
  • Blue Dream
  • Banana Candy Kush

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Customer Experience

With more than 10,000 reviews, Diamond CBD’s reputation is not in question.

While reviews vary widely from one product and brand to another, most tend to agree on one thing − they can definitely feel a buzz after just a few hits.

As expected, most buyers also rave about Diamond CBD’s discounts, and we agree their current 50% OFF deal (just for registering) is hard to match.



  • Overwhelming product choices

5. 3Chi – Impressive Selection of THC-high Delta 8 Strains

And while 3Chi doesn’t give much in the way of discounts, you’ll still see it recommended in many Reddit threads, which goes to show how good their products are.

3Chi shakes the industry up in a good way by providing customers with a selection of some of the most relaxing Delta 8 THC vape pens and cart options available.

Besides being natural and lab-tested, what sets 3Chi’s carts apart is the remarkable variety of strains.

Not only can you choose between Sativa, Indica, and Hybrid…

But there are actually 51 (not a typo) strains to choose from, all with unique effects and flavors − and all federally legal.

And if that’s still not enough for you…

You can also try their Focused Blends, which include Calm, Focus, Happy, and Soothe.

How’s that for choice?

Their best flavors include

  • Grape Ape
  • Purple Punch
  • Tangy
  • Blue Dream

>> Check out 3Chi’s unique focused blends on the official website >>

Customer experience

As mentioned above, 3Chi is recommended in many Reddit threads.

But that’s not all − their Delta 8 carts have also received 1,300+ reviews, with most users saying 3Chi carts are the “closest they can find to the real deal… well, that is legal anyway”.

Of course, everyone raves about the huge variety of strains and natural flavors, and some even use the carts as a natural remedy for lack of appetite, anxiety, and insomnia.


  • Reddit favorite
  • 51 (!) strains
  • Focused blends for specific effects
  • Transparent manufacturing methods
  • Third-party lab results


  • Not many discounts

6. Moonwlkr – Cheap Delta 8 THC Carts

Moonwlkr is a nice budget option for people who need their THC fix without spending a huge amount on vaping carts. 

For just $39.99, you can get 800 mg of Delta 8 THC in delicious Strawberry Gelato or Grape Runtz flavors.

But for an even better deal, the company runs regular promotions on its site, along with custom bundles that help you save an extra 25% OFF for mix-and-matching different vapes.

What also makes the Delta 8 THC vape cartridges interesting is that they contain 0.00% THC to be federally legal, but they still include natural terpenes to get that “real” taste.

If you’ve tried some carts and found them harsh…

Then you’ll appreciate the custom ceramic heater that comes with every Moonwklr cart. Because this heater is made for hemp (as opposed to nicotine), it helps make these ones of the smoothest carts available.

And obviously, all their products are third-party lab tested, free of VG, PG, PEG, vitamin E, and other harmful ingredients.

Here are their available flavors:

  • Himalia
  • Telesto
  • Titan

>> Check out Moonwlkr’s cheap carts (official website) >>

Customer Experience

Cheap doesn’t have to mean poor quality, and in Moonwlkr’s case, most customers are very happy with their CBD products.

From the ones who say the carts don’t make them cough as much as other brands to the ones lauding the unique taste and smooth hit − everyone seems to find what they’re looking for.


  • Free shipping available
  • Nice THC & CBD product selection 
  • Regular promos & discounts 
  • Very smooth hit
  • Food grade silicone


  • Needs more vape flavor variety

7. Just Delta 8 – Strongest Delta 8 Carts (Almost)

Just Delta 8 is a company that specializes in THC edibles. However, their vape cartridge game is nothing short of amazing.

In spite of the lack of flavor selection in their inventory, you’ll be glad to know that they offer some of the strongest vape carts out there, with 1000 mg of THC − just like Delta Extrax.

The 30-day satisfaction guarantee is great considering their products are very cheap − we really weren’t expecting this level of customer service.

Like other brands on our list, Just Delta 8 lets you choose between Sativa, Indica, and Hybrid carts so that you can get relaxing or energizing effects.

And if you want to check the Delta 8 carts’ quality for yourself…

You can go to the Lab Reports section of the website, where you’ll have access to all the independent lab testing results

To top it all off, they offer a generous 30% OFF on your first order, which is more than most.

Here are their flavors:

  • Pineapple Express
  • Strawberry Cough
  • Zkittlez

>> Get 30% OFF strong Delta 8 carts on Just Delta 8 (official site) >>

Customer Experience

Right off the bat, most reviewers say that the one thing they love about Just Delta’s carts is the fact they don’t get clogged like other brands.

Additionally, many like to use these carts for bedtime, to be able to relax and get a good night’s sleep.



  • Only three flavors

8. Binoid – Stringently Tested Delta Eight Carts

While Binoid is number 8 on our list, don’t think this means their products are low-quality.

In fact, all of Binoid’s products are made in a cGMP-certified manufacturing facility. In other words, they have to follow strict manufacturing standards before their products hit the market.

But that’s not all.

Their products are also tested 5 times and contain no harmful substances like vitamin E acetate. Some of you will also be glad to know that their products are Kosher Certified by Oregon DOA.

But enough said about quality control. Let’s talk about what the carts can do for you.

Available in 15 strains and flavors, their Delta 8 THC carts are also quite potent at 1 g per ml.

If you’ve read what I wrote before, then you’ll understand that this means Binoid is a good balance between 3Chi and Delta Extrax − a great strain variety, but still potent.

As a nice bonus, you’ll find that some products are often discounted. For instance, the Delta-8 carts are currently sold at a 30% discount (without you doing anything).

Some of their popular flavors include:

  • Lemon Haze
  • Grand Daddy Purp
  • Strawberry Lemonade
  • Sour Diesel

>> Check out Binoid’s cGMP-certified carts on the official website >>

Customer Experience

With 800+ reviews on their carts, it took us a long time to find out what customers think about Binoid.

But after all this work, it became evident that customers love their carts overall.

Most use them to get a deep relaxation at home, potentially before bed. While others use them to get “high”.

But all seem to love the brand for its low prices and frequent discounts − and the fact they didn’t run into shipping issues as they did with other companies.



  • No money-back guarantee
  • Not as well-known

9. Boston Hemp – Best Bulk Prices on Potent Delta 8 THC Carts

Boston Hemp is a great brand if you’re on a budget or you plan to order an impressive quantity of Delta 8 THC products and bundles.

The company regularly runs promotions on its website, especially for bulk orders, so they’re ideal to stock up.

When it comes to transparency, you could hardly ask for more − as the lab reports are directly available on the product page.

Unfortunately, the reputable brand offers only 2 flavors of Delta-8 carts but at least they have a good potency (900+ mg of Delta 8 THC per 1 ml).

  • Jack Herer
  • AK Therapy

>> Check out Boston Hemp’s great bulk discounts on the official site >>

Customer Experience

Most customers are pleased with Boston Hemp’s carts and particularly the fast and free shipping.

As expected, many reviewers say that Boston Hemp’s bundle deals are a great way to stock up, with up to a 33% discount on retail prices.


  • Good wholesale discounts
  • Certified lab tests
  • Quite potent (900 mg)
  • Free shipping 


  • Requires bulk purchase to enjoy discounts
  • Not many flavors

10. Secret Nature CBD – Artisanal Delta 8 THC Cart Brand

If you are looking for an all-natural Delta 8 with an artisanal twist, then we recommend you check out Secret Nature CBD and everything they have in store.

Primarily focusing on joints and vape products, each artisanal product is manufactured with care and tested by third-party labs.

However, as a smaller brand, they don’t give as much information on their products, and they don’t provide any money-back guarantee.

Some of their best sellers include:

  • Forbidden Fruit
  • White Fire OG
  • Lemon Diesel

>> Check out Secret Nature’s artisanal carts (official website) >>

Customer Experience

To be honest, we were surprised to see that their Delta 8 THC carts have received 500+ official website customer reviews, considering the little information they give and the fact that they’re a small company.

From these reviews, it seems that their carts are good for a mellow high, with a “meditative” feeling to focus and get things done, as well as potential health benefits such as pain relief.


  • Artisanal cannabis products
  • 500+ reviews
  • Third-party lab tested


  • Pricey
  • No money-back guarantee

How We Chose the Best Delta 8 Cart Brands

It’s no surprise that each company producing THC vape cartridges touts its products as the “highest quality” stuff that you can get right now. 

However, not all products in the cannabis industry are made equal, which is why we made sure that we set standards when selecting the best Delta 8 carts to include in our list:

Quality Control

The Delta 8 THC vape carts that we’ve reviewed—and the companies that sell them—provide only the best product quality you can get. Not to mention that these vape cartridges are made with high-quality ingredients that perform when you need or want them to.

Brand Reputation

A brand’s reputation is a strong indication of its product quality. Therefore, we’ve scoured the internet to see what customers had to say about each brand’s Delta 8 THC cartridges. From these, we then determined if the marketing matched the actual products and services.

Manufacturing Process

From third-party lab testing to synthetic additives all the way to lab test results. We made sure that the only Delta 8 THC vape cartridges on our list are from the best Delta 8 brands in the vaping industry.

Customer Service and Reviews

While most brands offer free shipping, we paid particular attention to those who back their claims with actions. In other words, brands that have a strong money-back guarantee and fast, helpful customer service team are ranked higher.

On the same note, we checked many customer reviews on independent websites such as Trustpilot and Reddit to see what actual buyers think of the carts.


We only included brands that use USA-grown, organic hemp plants (no pesticides or herbicides) to make their products.

Not only that, but we also made sure that the vape carts don’t contain any harmful additives, vitamin E acetate, or any artificial ingredients. And of course, we didn’t only take the brand’s word for it − we checked the lab test results.

What’s The Best Delta 8 THC Cartridge? − Buying Guide

Choosing the right Delta 8 product doesn’t just start and end with the flavor of your vape cartridge.

Below, you will find the criteria you have to consider to find the perfect THC cart for your needs.

High-Quality Materials

You should only get your Delta 8 THC carts from reputed sources like the ones we’ve listed in this article.

One important thing to consider is that not only should you make sure that the THC content is legit, but the materials used for the cartridges themselves are of the highest quality.

Ensure that your carts use stainless steel casings with a ceramic heater inside to ensure safe and lasting use.


Companies like Exhale, BudPop, and Delta Extrax—just to name a few—are places where you can find legitimate, high-quality Delta 8 vaping carts. 

Don’t fall for cheap ones from shady companies, which are most likely unsafe for use. As the old saying goes: if it’s too good to be true


Laboratory tests done by third parties are indicators that you’re getting a product that’s safe, legal, and has top-shelf quality.

Companies in the THC and CBD game are almost always transparent with the kind of tests and certifications their quality products have, so only get your Delta 8 carts from these places.

Vape Juice Color

A surefire way to tell that you’re getting an inferior – and even hazardous – product is by looking at the vaping liquid itself.

Quality Delta 8 THC vape juices and liquids must always be clear. If it’s tinted green, purple, red, or brown, then you should avoid these types of bush-league D8s.

Best Delta 8 THC Carts and Brands − FAQ

What Are Delta 8 Carts?

Delta 8 carts are vape cartridges that contain Delta 8 THC – which is a federally legal substance extracted from cannabis plants. Much like regular vape pens, you’ll need a vaping device to use these carts properly.

Unlike smoking cannabis buds, using vape carts eliminates unwanted refuse like smoke, odor, and ash when getting your THC fix.

How Should I Store My Delta 8 Carts?

TIt’s best to store Delta 8 carts in a cool, dark place that’s away from direct sunlight. If you have a designated container for them—that’s even better.

Delta 8 carts aren’t cheap, so it’s important that you properly take care of them to ensure their longevity.

Just remember these three tips:

  • Avoid direct sunlight
  • Avoid extreme temperatures
  • Avoid exposing the vape oil to the air

What Is Delta 8?

Simply put, Delta 8 THC is a type of cannabinoid found in marijuana and is very similar to Delta 9. It’s commonly sold as either vape pens, gummies, carts, or, preferably, organic hemp flowers.

Delta 8 is quickly becoming a big name in the cannabis industry due to its potential beneficial properties and minimal side effects, and of course, the fact that it’s legal in most states.

However, Delta 8 is a far less potent version than its cousin Delta 9. 

Is Delta 8 THC Legal?

Yes, Delta 8 THC is legal.

Though some states have banned the substance due to many different reasons. Those states include: 

Alaska, Colorado, Delaware, Idaho, Iowa, Montana, New York, Nevada, North Dakota, Oregon, Rhode Island, Vermont, Utah, and Washington.

Are Delta 8 Carts Legal?

Yes, Delta 8 carts are legal unless you live in a restrictive state. 

Indeed, although most states in the U.S. have opened up their laws and statutes to legalize Delta 8 and cannabis products in general – there are still some places where it’s still illegal

Find them below:

Alaska, Colorado, Delaware, Idaho, Iowa, Montana, New York, Nevada, North Dakota, Rhode Island, Vermont, Utah, and Washington (except DC).

Is Delta 8 Safe?

As long as you use high-quality products that have been guaranteed to be all-organic, then the use of D8 is mostly safe. Problems arise from less-than-stellar manufacturers infusing their products with contaminants and artificial ingredients when extracting cannabinoids from cannabis plants.

However, the online sellers we’ve provided you, like Exhale, use none of those, so you should be fine if you choose to go with any of them!

Does Delta 8 Show Up in a Drug Test?

Yes, Delta 8 shows up in drug tests. That’s because standard drug tests today have no way of differentiating Delta 8 cannabinoids (which are legal) from Delta 9 (the active compound that gets you high and is still illegal).

Therefore, if you have a drug test coming up, you should avoid consuming Delta 8 at least 4 weeks prior − whether it’s legal in your state or not.

Which Is the Strongest Delta 8 Cart Available?

The strongest Delta 8 cart available is Delta Extrax’s Cali Orange Kush, in our opinion. This is one of the most intense vape pens that you can find right now, with high Delta 8 THC content.

Can Delta 8 Carts Get You High?

Yes, Delta-8 carts can get you high. However, Delta 8 THC generally makes you feel calmer compared to Delta 9 THC, which is the active compound when you smoke buds.

In other words, Delta 8—no matter how intense the content in the cart is—provides you with a smaller risk of feeling tension or paranoia when you use it.

What are the Best Delta 8 Carts − Final Words

The vaping industry is pretty huge, and with so many different sellers out there, it’s challenging to know which hemp market to trust. 

But with companies like Exhale Wellness, Delta Extrax, and BudPop, getting the best Delta 8 carts is now an easy task.

These sellers provide you with nothing but the most legitimate and potent products available in the cannabis market today.

Not to mention that they are all lab-tested to make sure they are federally legal and free of harmful chemicals.

Whichever brand you decide to go with, just remember to always stay safe − and if you go for a brand not included in this list, please always make sure to thoroughly check its reputation beforehand.

Hopefully, this guide helped you pick the best brand for you; good luck!

Disclaimer: This article does not provide medical advice.

The information, including but not limited to text, graphics, images, and other material contained in this article, are for informational purposes only. No material within this article is intended to be a substitute for professional medical advice, diagnosis, or treatment.

Always speak to your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undertaking a new health care regimen, and never disregard professional medical advice or delay seeking it because of something you read in this article. 

The Impact of Cannabis Use on Medication Nonadherence in Psychiatry – Psychiatric Times

Medication nonadherence has been one of the major barriers in patient care for psychiatrists managing patients with chronic mental health disorders.1 This has resulted in multiple negative outcomes including a protracted course of illness, worsening disease symptoms severity, risk of relapse suicide risk, illness exacerbation, mortality, and frequent hospitalizations.2 In addiction, medication nonadherence-related hospital readmissions increased the health care cost burden of the early 21st century to more than $100 billion per year, continuing to rise annually.3 However, one of the modifiable risk factors for medication nonadherence with possible interventions gaining traction is substance use disorder (SUD), particularly cannabis use disorder (CUD).4

Cannabis is one of the most frequently used drugs worldwide, and CUD has been rising substantially globally, especially in the Americas and Asia.5 CUD has become a growing problem in the United States since the passing of legislation permitting the medical use of cannabis in more than 33 states and recreational use in 11 additional states as of 2020.6 The overall percentage of patients who are nonadherent to their psychotropic medication was estimated to be 49% (56% with schizophrenia, 50% with major depressive disorders, and 44% with bipolar disorders).7,8 A recent study found that patients with first-episode psychosis who use cannabis were more prone to medication nonadherence and illness relapses compared to those who stopped using substances.9 A systematic review of 3678 patients with psychiatric illnesses also found cannabis users to have 2.5 times higher medication nonadherence to antipsychotic medications compared to non-cannabis users.4

Nonadherence is very challenging to tackle in the clinical setting, given its high prevalence. Nonadherence is usually identified after multiple relapses, misinterpretation data of medication efficacy, and several changes to prescription medications.10 However, there is evidence that cannabis use can be an early warning sign for future nonadherence and may be a good source for early intervention before a patient relapses.4

Typically, a urine drug screen (UDS) is done for screening patients who might have been using cannabis for several weeks in cases of chronic cannabis use. Delta-9-tetrahydrocannabinol (THC) and other cannabinoids metabolites can be detected in the urine of chronic heavy users of cannabis for up to 6 weeks. However, other active cannabinoids such as cannabidiol have less sensitivity to testing. What is crucial for clinicians to know is that a therapeutic alliance between the physician and the patient is key to managing patients with cannabis use and medication nonadherence.

Despite the availability of UDS tests, physicians should feel comfortable asking their patients about history of drug use utilizing techniques such as motivational interviewing. The interaction of cannabis and psychotropic medications should be described in clear terms to patients. Evidence has shown that the efficacy of antipsychotics in patients with psychosis and comorbid cannabis use is limited in the treatment of psychosis.11 There should be intentional education for patients about the negative effects of cannabis use. Clinicians must understand that CUD, like other SUDs, is a chronic relapsing disorder and some patients may have a difficult time attaining or maintaining sobriety. Sometimes it is helpful to offer patients shorter appointments to monitor periods of sobriety or complete abstinence during their treatment course. This also goes a long way to make patients feel like part of their treatment decisions.

Here we present 2 cases of patients with a history of chronic cannabis use and medication nonadherence to highlight the need for clinicians to spend more time educating their patients about substance use and offer other interventions to increase chances of abstinence.

Case Vignette 1

“Ms Monroe” is a young female patient with a history of anxiety disorder and major depressive disorder. Ms Monroe was diagnosed and prescribed with antidepressants and anxiolytic in the outpatient setting but reported multiple relapses due to poor compliance with her medications and heavy daily use of cannabis. She feels that smoking cannabis gives her relief from symptoms of anxiety and depression. Her increased use of cannabis over the years resulted in further deterioration of her mental health, as she was reported to be very paranoid and acting bizarre at presentation.

In the ER, she initially had hallucinations, then suddenly became completely mute and did not participate in any assessment. Ms Monroe was admitted to the inpatient, placed on appropriate precautions for the initial portion of hospitalization, and introduced to a therapeutic milieu. All labs and imaging studies were found to be within normal limit. She was diagnosed with catatonia. Ms Monroe responded to Ativan challenge and Ativan along with the addition of an antidepressants and antipsychotics. She responded well to the treatment, her catatonia completely resolved, her psychotic symptoms lessened, and her oral intake improved. While on the unit, she actively engaged in all aspects of treatment including individual and group/milieu therapy. Ms Monroe was educated about the negative physical and emotional effects of cannabis use. The team recommended she stop due to possible exacerbation of psychotic symptoms and concern for effects on efficacy of her medications. Motivational interviewing was employed and found to be very helpful. A significant improvement in patient insight regarding medication adherence and adverse effects of cannabis use was appreciated at the time of discharge.

Case Vignette 2

“Mr Walker” is a middle-aged male patient diagnosed with schizophrenia. Mr Walker was treated with antipsychotics for several years. He has a history of multiple relapses and hospitalization in the context of poor medication adherence and chronic cannabis use. Each time this patient is discharged with antipsychotic medications, he defaults on his care and goes back on the street to acquire street-available marijuana. His chronic cannabis use has often resulted in a relapse and therefore made him a frequent user of the mental health facility closest to him.

During his most recent admission, Mr Walker was asked if he would continue to use cannabis. He stated that he would not be able to say definitively until discharge from the hospital. Mr Walker was initially adamant about his care in the hospital but later started to participate in the treatment plan on the inpatient service. He was offered individual and group therapy sessions along with restarting his psychiatric medications. He was able to meet with the drug and alcohol use counsellor, who, over the duration of his stay in the hospital, was able to speak to him about quitting cannabis use, given his history of relapse and multiple hospitalizations. Different modalities were employed, including counseling, and scheduling short outpatient clinic appointments. At discharge, Mr Walker was sober and willing to engage with his psychiatric treatment while staying sober. He had a better insight into his psychiatric condition and understood the need to stop taking cannabis and be adherent to medication to prevent subsequent hospital admissions.


These 2 cases bring to light poor insight into a major issue among these patients. Often, patients do not think cannabis has anything to do with their mental illness. If anything, they think it helps their current mental health status improve. If clinicians spend more time educating their patients about substance use, its effects, and interactions with their medications, negative outcomes might be prevented. Both patients in these cases responded to antipsychotic and therapeutic milieu, but the problem is that patients often relapse once they get back on cannabis.

Different approaches have been implemented to improve psychotropic medication adherence among patients with chronic cannabis use. These include motivational interviewing (MI), cognitive behavioral therapy (CBT), use of smartphone apps, and augmentation with telepsychiatry. Implementation of evidence-based MI Style Adherence Therapy was found to be clinically significant in improving adherence to psychotropic medication (82% to 85%) in a Veterans Affairs Mental Health Clinic.12 MI intervention has shown improvement in psychotropic medication adherence from 43.9% to 70.7% in adolescents taking antidepressants and mood stabilizers.13

The usage of CBT strategies has shown to improve medication adherence and treatment outcomes in patients with bipolar disorder by increasing knowledge about medication and changing attitude toward treatment.14 Moreover, CBT use in another bipolar population study was shown to increase medication adherence and reduce relapse rates.15 Another study explored a combination of medication monitoring and CBT in increasing medication compliance in patients with bipolar disorder and comorbid SUD over 12 weeks compared to medication monitoring alone.16 The study found that adding CBT showed improved medication adherence and mood symptoms.16

Another possible intervention could be smartphone appsin using different modalities to enhance medication adherence. For instance, a study explored the use of smartphone app intervention in managing patients with type 2 diabetes medication nonadherence.17 The study showed that the smartphone app was user-friendly and had improved awareness of medication adherence. However, the app usage did not improve clinical outcomes in the population. The usage of smartphone apps in assisting with mental health medications adherence is still in its infancy due to lack of an evidence-based approach and the need for cocreation with patients, which might increase the impact on medication nonadherence. The lack of social cognition models in ensuring patients’ education, motivation, skills, beliefs, and type of adherence while developing the apps makes it very challenging to use in mental health interventions.18 A systematic review of 13 articles assessing the studies that investigated these apps showed a lack of standardized measures of adherence.19

Finally, another approach that could be beneficial is telepsychiatry. A recent systematic review including 17 articles showed that telemedicine improved medication adherence in patients with depression, bipolar disorder, or schizophrenia.20 Telemedicine, such as telephone call and text messaging intervention, has been shown to improve medication adherence in patients with severe mental illnesses,21 but not much research has been done to see if it can help patients with CUD. However, a randomized controlled trial found that using text messages as reminders may contribute to improving medication adherence in patients with comorbid depression and substance use.22 More research needs to explore patients with mental health conditions and comorbid cannabis use disorder, given the impact of cannabis on medication adherence.

Concluding Thoughts

Treating mental illness when patients are medication-nonadherent in the context of cannabis use is a complex process. Choosing the right intervention is important, as psychopharmacology, MI, CBT, telepsychiatry, and smartphone app interventions each pose their own individual challenges. In addition, factors that also influence medication adherence in CUD such as treatment modalities, self-motivation to treatment, self-coping capacity, and social support to influence changing behavior are things to consider when hoping for change.

Multiple research approaches have provided evidence-based findings, including integrated and multifaceted approaches to help and support current practices, but further research is needed as current options continue to pose implementation challenges.

Dr Oladunjoye is a psychiatry resident physician in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, Texas. Dr Ahmed is a psychiatry resident physician in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, Texas. Dr Murtaza is a psychiatry resident physician in the Menninger Department of Psychiatry and Behavioral Sciences at Baylor College of Medicine in Houston, Texas. Dr Jegede is an attending physician and assistant professor of psychiatry at Yale School of Medicine in New Haven, Connecticut.

If you’re interested in hearing more about cannabis, there’s still time to register for the 2022 Annual Psychiatric Times™ World CME Conference.


1. Devine F, Edwards T, Feldman SR. Barriers to treatment: describing them from a different perspective. Patient Prefer Adherence. 2018;12:129-133.

2. Higashi K, Medic G, Littlewood KJ, et al. Medication adherence in schizophrenia: factors influencing adherence and consequences of nonadherence, a systematic literature review. Ther Adv Psychopharmacol. 2013;3(4):200-218.

3. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487-497.

4. Foglia E, Schoeler T, Klamerus E, et al. Cannabis use and adherence to antipsychotic medication: a systematic review and meta-analysis. Psychol Med. 2017;47(10):1691-1705.

5. UNODC. United nations office on drugs and crime. world drug report 2017. 2017. Accessed August 5, 2022.

6. Map of marijuana legality by state. DISA Global Solutions. 2020. Accessed August 5, 2022.

7. Semahegn A, Torpey K, Manu A, et al. Psychotropic medication non-adherence and its associated factors among patients with major psychiatric disorders: a systematic review and meta-analysis. Syst Rev. 2020;9(1):17.

8. Oladunjoye AF, Kaleem SZ, Suresh A, et al. Cannabis use and medication nonadherence in bipolar disorder: a nationwide inpatient sample database analysis. J Affect Disord. 2022;299:174-179.

9. Schoeler T, Petros N, Di Forti M, et al. Effect of continued cannabis use on medication adherence in the first two years following onset of psychosis. Psychiatry Res. 2017;255:36-41.

10. Cramer JA, Rosenheck R. Compliance with medication regimens for mental and physical disorders. Psychiatr Serv. 1998;49(2):196-201.

11. Wilson RP, Bhattacharyya S. Antipsychotic efficacy in psychosis with co-morbid cannabis misuse: a systematic review. J Psychopharmacol. 2016;30(2):99-111.

12. Hughes F, Vess J, Johnson E. Increase adherence to psychotropic medication through motivational adherence therapy: a quality improvement project. Issues Ment Health Nurs. 2018;39(8):709-713.

13. Hamrin V, Iennaco JD. Evaluation of motivational interviewing to improve psychotropic medication adherence in adolescents. J Child Adolesc Psychopharmacol. 2017;27(2):148-159.

14. Cochran SD. Preventing medical noncompliance in the outpatient treatment of bipolar affective disorders. J Consult Clin Psychol. 1984;52(5):873-878.

15. Lam DH, McCrone P, Wright K, Kerr N. Cost-effectiveness of relapse-prevention cognitive therapy for bipolar disorder: 30-month study. Br J Psychiatry. 2005;186(6):500-506.

16. Schmitz JM, Averill P, Sayre S, et al. Cognitive-behavioral treatment of bipolar disorder and substance abuse: a preliminary randomized study. Addictive Disorders & Their Treatment. 2002;1(1):17-24.

17. Huang Z, Tan E, Lum E, et al. A smartphone app to improve medication adherence in patients with type 2 diabetes in Asia: feasibility randomized controlled trial. JMIR Mhealth Uhealth. 2019;7(9):e14914.

18. Kassianos AP, Georgiou G, Papaconstantinou EP, et al. Smartphone applications for educating and helping non-motivating patients adhere to medication that treats mental health conditions: aims and functioning. Front Psychol. 2017;8:1769.

19. Patoz M-C, Hidalgo-Mazzei D, Pereira B, et al. Patients’ adherence to smartphone apps in the management of bipolar disorder: a systematic review. Int J Bipolar Disord. 2021;9(1):19.

20. Basit SA, Mathews N, Kunik ME. Telemedicine interventions for medication adherence in mental illness: a systematic review. Gen Hosp Psychiatry. 2020;62:28-36.

21. Schulze LN, Stentzel U, Leipert J, et al. Improving medication adherence with telemedicine for adults with severe mental illness. Psychiatr Serv. 2019;70(3):225-228.

22. Agyapong VI, Ahern S, McLoughlin DM, Farren CK. Supportive text messaging for depression and comorbid alcohol use disorder: single-blind randomised trial. J Affect Disord. 2012;141(2-3):168-176.

These 2 college friends pawned watches and cars to fund their cannabis startup—it could bring in $400 million this year – CNBC

Pouring your hard-earned money and time into a new business idea can be terrifying, even for experienced entrepreneurs. For Lukasz Tracz and Sebastian Solano, their second attempt at it nearly broke them.

Tracz, 37, and Solano, 38, are co-CEOs and co-founders of Jeeter, a Desert Hot Springs, California-based cannabis brand they launched in 2018 with their siblings — together, they’re part of two sets of twins. In just four years, Tracz and Solano have built Jeeter into one of the cannabis industry’s most successful retail brands, selling more pre-rolled joints than any other brand in the market.

In 2019, Jeeter made $19 million in total revenue, according to the company. That number is poised to jump exponentially this year: The company projects sales of more than $400 million in 2022. Just wrap your mind around this fact: In the brand’s home state of California, customers smoke about 3.5 million Jeeter pre-rolls each month, the company says.

To get Jeeter off the ground, though, Tracz and Solano tell CNBC Make It they had to learn some things the hard way. A series of false starts in a new industry meant that the first two years of trying to establish Jeeter — even as the company brought in millions — were „some of the toughest, worst years of our life,” Solano says.

Tracz adds that, at one point, the founders pawned their watches and cars to get enough money to cover payroll after burning through millions of dollars in funding before Jeeter took off.

Here’s how they did it, and why they say Jeeter could become a billion-dollar brand in the next few years.

’Ridiculous’ party people

In a way, it’s deja vu all over again for Tracz, Solano and their twin siblings — Patryck Tracz and David Solano, who serve as Jeeter’s vice president of marketing and chief sales officer, respectively. As college students at Florida State University in 2006, the quartet threw a series of parties that eventually became Life in Color, a multimillion-dollar global events and music festival brand.

Tracz and Solano met while waiting tables to pay their way through college roughly 16 years ago. Together with their twins, the four bonded over watching HBO’s „Entourage.” The show inspired them to look for ways to make money while partying together, so they started throwing house parties.

Far from small shindigs, Solano says these „ridiculous” parties would attract hundreds of college kids, some paying up to $150 to board a chartered bus and be shepherded to local nightclubs and back again.

After initially funding the parties with money they’d made from previous events, the friends used ticket sales and sponsorship cash to move into nightclubs and sports arenas. Life in Color became a legitimate business — touring the country with paint cannons and electronic music acts — before the co-founders sold it to Los Angeles-based events group SFX entertainment in 2012 for an undisclosed amount.

Rapper Ludacris performs at Jeeterday in November 2021.

Source: Jeeter

Tracz and Solano stayed onboard as partners at SFX for five years. The ride was bumpy — SFX declared bankruptcy in early 2016 — and Solano says the „very corporate” environment weighed on all of them.

At the time, Solano says, the co-founders were receiving unsolicited pitches from cannabis startups looking for investors. By then, legal marijuana was already a multibillion-dollar industry, and California represented its most fertile ground.

Solano says he decided to „dive into the numbers” and found an „outrageous” opportunity: The company with the buzziest, most attractive brand might have the best chance of winning over a nascent market. The friends pooled their money to launch their own cannabis brand, cobbling together $6 million between their own savings and some additional funding from friends and family.

They were distinctly outside of their comfort zone this time. „Everything was a challenge,” Tracz says.

From running out of cash to building up buzz

First, the quartet struggled to settle on what area of the cannabis industry they should focus on. Should they get into cultivation, retail or both? Should they try to sell whole flower — the actual cannabis plant — or distilled oil?

A rapidly growing industry didn’t help: Solano says their plans changed „every six months.” After a year of false starts, he says they finally decided to keep it simple: Source cannabis flower from licensed cultivators and hire employees to hand-roll joints.

The point, after all, wasn’t to get lost in the weeds of the cannabis industry. It was to build a brand. The company’s name was a starting point: „Jeeter” is a Southern Florida slang term for a marijuana joint.

The company promises that each of its joints is hand-rolled — a unique touch that requires a lot of hands, which is why Jeeter now has 1,156 employees turning out 145,000 joints per day in its Desert Hot Springs, California, factory.

That’s an expensive approach, and by the time the co-founders settled on their concept, they’d nearly run out of their $6 million in funding. They were also slowed by the red tape needed to acquire the required licenses and approvals to sell cannabis products to consumers.

„There’s just so many steps that were out of our ballpark,” Tracz says. „We’re used to throwing parties and we’re not used to, like, getting land and real estate and getting zoned for cannabis and all of that stuff.”

In 2019, Jeeter took out a $500,000 loan to stay afloat. The company brought in roughly $19 million in revenue that year, the company says, but Solano admits much of that came from selling cannabis wholesale from cultivators to dispensaries — essentially, acting as middlemen — rather than from Jeeter’s joints.

All along, Tracz and Solano walked „door to door” to pitch their joints to marijuana dispensaries and befriend each establishment’s staff members, or „budtenders.” They created exclusive product drops, one-time event pop-ups and limited-edition offerings of joints in collectible packaging. Eventually, they leveraged their entertainment connections to find celebrity partners for those drops, including athletes Dwayne Wade and Ricky Williams.

As the buzz grew, so did Jeeter’s revenue: $80 million in 2020 and $180 million in 2021, which is also when Jeeter became profitable, the company says. Solano says 99% of this year’s projected sales will come from Jeeter’s branded products, not wholesale. With a straight face, he expects Jeeter to top $1 billion in annual sales by 2025.

That’s a tall ask. Only a handful of cannabis companies are known to bring in 10 figures in annual revenue, and Jeeter is currently only active in three of the 19 total U.S. states with legal recreational marijuana sales: Arizona, California and Michigan.

Solano says the plan involves expanding into more states and new markets like apparel and merchandise. It also means doubling down on the founders’ longtime specialty: events. Last year, for example, the company hosted its first „Jeeterday,” featuring product drops and appearances by celebrities like Wade, Demi Lovato and Ludacris.

From concerts to product drops, successful events aim „to connect with consumers on that more intimate level of giving them a real experience,” Solano says. „You’re not just smoking Jeeter, but you’re smoking Jeeter and we’re creating this whole world for you.”

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Weedmaps for Business debuts as a SaaS suite for cannabis retailers and brands – TechCrunch

Veteran cannabis tech company WM Technology is rebranding and expanding its SaaS offering to move upstream beyond its existing Weedmaps marketplace. Previously known as WM Business, this B2B subscription-based suite will now be known as Weedmaps for Business, a service designed to offer an end-to-end solution for cannabis retailers and brands.

Due to regulatory restrictions and stigma, cannabis businesses can’t operate as freely as their peers in other sectors: From ads to payments and delivery, they require dedicated tools to comply with fragmented legislation, both in the U.S. and Canada. But the more tools they require, the more complex things become.

That’s where Weedmaps for Business hopes to step in.

The service is more integrated than its predecessor, CEO Chris Beals told TechCrunch. This evolution, he said, is based on the company identifying, “a need for a unified set of tools that would help retailers and brands with the lifecycle of how they reach, convert, retain consumers — but also how they get insights and analytics around that lifecycle.”

Christopher Fenske, chief strategy officer at California-based dispensary Jaderoom, confirmed that a lack of integration was a pain point for dispensaries, saying that, “the biggest hurdle in the cannabis industry right now is connecting all the software seamlessly between your CRM, orders fulfillment and delivery management system.”

Weedmaps for Business aims to be a full SaaS suite, in part thanks to integrating the offering of several companies WM Technology acquired since it went public on the Nasdaq via a SPAC under the MAPS ticker in July 2021.

“What we now have,” Beals told TechCrunch, “is the culmination of several years of acquisition and M&A work, integration work and shared feature work such that businesses can now go and buy once and log into this first full platform offering for consumer lifecycle management.”

Each of WM’s recent acquisitions have turned into elements of the suite: Sprout, into WM CRM; Enlighten, into advertising-centric WM Adsuite & WM Screens; logistics-focused Cannveya, into WM Dispatch; and CannCurrent, into WM Connectors, which Beals referred to as a “Zapier for cannabis.”

All in all, WM Technology’s ambition is to support retailers and brands at every stage in the consumer funnel. In a similar move, Oregon-based Dutchie recently launched Dutchie Pay to help dispensaries accept cashless payments.

Integrated suites are particularly relevant in the cannabis sector, Beals said. “Cannabis is an incredibly highly regulated space and so the laws and regulations vary widely from state to state and in some places from city to city. The ability for us to build compliance functions and then have them be seamlessly leveraged across the suite and handoff compliantly is a real advantage of having a centralized platform.”

Saving time and money matters more to dispensaries and cannabis brands than ever, as, “these businesses are suffering the effects of margin compression given that we’re in what appears to be a recessionary period,” the CEO added.

According to Beals, one of the main challenges for cannabis brands is that, “it’s incredibly difficult to reach actual high frequency cannabis consumers.”

Another issue that WM is hoping to help tackle is that “almost half of cannabis consumers don’t have a favorite brand.” As a result, “In cannabis, we haven’t seen the same level of the same ability of brands to generate increased premiums for brand affinity as we’ve seen in other consumer goods. But that’s going to change,” Beals hopes.

Better analytics and benchmarks data would also help brands maximize their profits. Weedmaps for Business already includes analytics elements, but the company is hoping to further expand that side of the suite over time.

“We’re looking to start adding information on Share of Voice, suggestions of products that seemed to be drawing increased consumer affinity, on skewed distributions by geographies. A lot of that data sits with us currently, it’s just a matter of building it into as we iterate on these analytical solutions,” Beals said.