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E-Cigarette & Vaporizer Market 2019, Trend, CAGR Status, Growth, Analysis and Forecast to 2024 – Montana Ledger

The company provides a detailed analysis of the market and future aspects of the E-Cigarette & Vaporizer Market. It focuses on critical and critical data that makes it a very important tool for research, experts, analysts, and managers to achieve ready-to-access analysis. The report provides an inclusive analysis of the E-Cigarette & Vaporizer market size forecast from 2018-2025.

Sample report can be viewed in a PDF form by visiting @

The report embraces the complete information of the key players involved in the worldwide E-Cigarette & Vaporizer market. In addition, it provides its market share by various regions with the company and product introduction and their position in the E-Cigarette & Vaporizer market. In addition, the report takes into account recent marketing developments as well as their marketing strategies along with an overall business overview. In addition, the report covers market growth factors and restraints of this market.

Prominent players of E-Cigarette & Vaporizer market:

  • Njoy
  • V2
  • International Vaporgroup
  • Vaporcorp
  • Electronic Cigarette International Group
  • Truvape
  • ProVape
  • Cigr8
  • KiK
  • Hangsen
  • FirstUnion
  • Shenzhen Jieshibo Technology
  • Innokin
  • Kimree
  • Product Type Coverage (Market Size & Forecast, Major Company of Product Type etc.):

  • E-Cigarette
  • Vaporizer
  • Application Coverage (Market Size & Forecast, Different Demand Market by Region, Main Consumer Profile etc.):

  • Male
  • Female
  • Regional Segmentation for E-Cigarette & Vaporizer market:

    There are 10 chapters to put on view for E-Cigarette & Vaporizer market:

    Chapter 1: Consumption by Regions

    Chapter 2: Production, By Types, Revenue and Market share by Types

    Chapter 3: Consumption, By Applications, Market share (%) and Growth Rate by Applications

    Chapter 4: Complete profiling and analysis of Manufacturers

    Chapter 5: Manufacturing cost analysis, Raw materials analysis, Region-wise manufacturing expenses

    Chapter 6: Industrial Chain, Sourcing Strategy and Downstream Buyers

    Chapter 7: Marketing Strategy Analysis, Distributors/Traders

    Chapter8: Market Effect Factors Analysis

    Chapter9: Market Forecast

    Chapter 10: E-Cigarette & Vaporizer Research Findings and Conclusion, Appendix, methodology and data source

    Check here for the [email protected]

    Customization of the Report:
    This report can be customized to meet the client’s requirements. Please connect with our sales team ([email protected]), who will ensure that you get a report that suits your needs.

China Lets Its Cannabis Industry Bloom but Says No to Marijuana – The Wall Street Journal

QUJING, China—In China, marijuana is seen as a dangerous narcotic, and possession is strictly punished. That hasn’t stopped the country from trying to become a powerhouse in the fast-growing industry for cannabis products.

China has grown hemp, a strain of cannabis, for thousands of years to use in clothing and traditional medicine and is one of the world’s largest hemp producers. The country is using that foothold to churn out cannabidiol, or CBD, a loosely regulated chemical related to marijuana that is finding its way into…

New Report: Men Prefer Medical Cannabis Strains High in THC – GlobeNewswire

NEW YORK, Nov. 12, 2019 (GLOBE NEWSWIRE) — RYAH Medtech, Inc. (“RYAH” or the “Company”), a big data and technology company focused on valuable predictive analysis in the global medical plant intake industry, has released a data analytics report on men and their use of medical cannabis. Surveying feedback from 35,069 men over a 22-month period, the report found that men make up approximately 55% of the medical cannabis patient population and men typically have higher levels of previous cannabis experience than females. Remarkably, the top ten health concerns reported by the men surveyed identically mirrored the conditions treated by women in the RYAH patient data pool, with the exception of ADHD.„Understanding each gender’s relationship with medical cannabis is critical for refining treatments and increasing successful patient outcomes. We were surprised to see that over 77.8% of the males surveyed were using medical cannabis for treatment on a daily or nearly daily basis and many of them had previously used cannabis for medical or recreational purposes. Since this differs significantly with the average female patient’s exposure, we hope that medical providers and researchers will be inspired to further study medical cannabis treatments that are personalized to achieve effective patient outcomes,” said Gregory Wagner, Chief Executive Officer of RYAH.The top ten medical concerns that the men reported included: anxiety, stress, depression, pain, insomnia, ADHD, mood swings, headaches, fatigue, and social anxiety—9 out of 10 being related to mental health. For their treatment, men preferred strains that are high in THC or a balance of THC:CBD and preferred consumption via smoking and vaporization. The report also went into some of the specific strains; for ADHD, men found relief with AC/DC (>1% THC, 20% CBD, Indica-dominant), Super Lemon Haze (>22% THC, <1% CBD, Sativa-dominant), Sour Tsunami, and Purple Candy (19% TCH, <1% CBD, Hybrid). For PTSD, men preferred Gorilla Glue, 3 Kings, Banana Kush, and Blueberry Cheesecake.The full report and related insights are available online at: RYAH Medtech, Inc.
RYAH is a big data and technology company focused on valuable predictive analysis in the global medical plant intake industry. Its robust artificial intelligence platform aggregates and correlates HIPAA-compliant medical data, which is intended to help doctors and patients personalize plant-based treatments to better predict treatment outcomes. The data collection is also relevant for growers, dispensaries and Licensed Processors (LPs) to monitor and manage plant strain effects on patients. With a strong IP portfolio, RYAH gathers deep and insightful data on the complete medical plant lifecycle, from seed to consumption.
Forward-Looking Statements
Certain statements contained in this press release constitute “forward-looking information” as such term is defined in applicable Canadian securities legislation and United States rules and regulation. The words “may”, “would”, “could”, “should”, “potential”, “will”, “seek”, “intend”, “plan”, “anticipate”, “believe”, “estimate”, “expect” and similar expressions as they relate to the Company; execution of additional distribution agreements; and the results users may receive from using RYAH are intended to identify forward-looking information. All statements other than statements of historical fact may be forward-looking information. Such statements reflect the Company’s current views and intentions with respect to future events, and current information available to the Company, and are subject to certain risks, uncertainties and assumptions. Many factors could cause the actual results, performance or achievements that may be expressed or implied by such forward-looking information to vary from those described herein should one or more of these risks or uncertainties materialize. These factors include, without limitation: the general business and economic conditions in the regions in which the Company operates; the ability of the Company to execute on key priorities, including the successful completion of acquisitions, business retention, and strategic plans and to attract, develop and retain key executives; difficulty integrating newly acquired businesses; the ability to implement business strategies and pursue business opportunities; disruptions in or attacks (including cyber-attacks) on the Company’s information technology, internet, network access or other voice or data communications systems or services; the evolution of various types of fraud or other criminal behavior to which the Company is exposed; the failure of third parties to comply with their obligations to the Company or its affiliates; the impact of new and changes to, or application of, current laws and regulations; a novel business model; granting of permits and licenses in a highly regulated business; the overall difficult litigation environment, including in the United States; increased competition; changes in foreign currency rates; increased funding costs and market volatility due to market illiquidity and competition for funding; the availability of funds and resources to pursue operations; critical accounting estimates and changes to accounting standards, policies, and methods used by the Company; the occurrence of natural and unnatural catastrophic events and claims resulting from such events; and the risk associated with a business in the cannabis industry. Should any factor affect the Company in an unexpected manner, or should assumptions underlying the forward-looking information prove incorrect, the actual results or events may differ materially from the results or events predicted. Any such forward-looking information is expressly qualified in its entirety by this cautionary statement. Moreover, the Company does not assume responsibility for the accuracy or completeness of such forward-looking information. The forward-looking information included in this press release is made as of the date of this press release and the Company undertakes no obligation to publicly update or revise any forward-looking information, other than as required by applicable law.
Public Relations Contact:
Annie Graf / Brittany Tibaldi
KCSA Strategic Communications /
786-390-2644 / 347-487-6794
Investor Relations Contact:
Elizabeth Barker
KCSA Strategic Communications

What is the difference between cannabidiol and THC? – Open Access Government

cannabidiol and THC© Tinnakorn Jorruang |

Dr Diana Gall (MD), GP at Doctor4U tells us the difference between cannabidiol and THC

Although both cannabidiol and THC come from the same plant, there are differences. Their chemical structure is the same with 21 carbon atoms, 30 hydrogen atoms and two oxygen atoms, however, the atoms are arranged differently and they affect the body differently. THC produces a high whereas cannabidiol does not. The psychoactive effects of THC are different for each person but generally, it will produce feelings of euphoria, relaxation, amusement, or anxiety. Both cannabidiol and THC have benefits, however, cannabidiol can provide the same benefits without the high which is more desirable when it is being used for medicinal purposes.

To what extent can CBD help improve individuals’ quality of life and well-being?

CBD is thought to have lots of health benefits, it has all of the qualities of the marijuana plant without the psychoactive effect from THC which gets you high. Of course, it’s important to remember that CBD affects everyone differently, not everyone will experience the benefits but some may find it’s a cure or a reliever for their ill-health. While CBD is still being researched and studied there is some strong evidence in support of the substance with many people reporting significant improvements in their health when taking CBD.

In particular, those who have long-term conditions have found that CBD is one way of managing their condition. CBD is used for medicinal purposes when every other medication or method of treatment for that particular condition has been exhausted and has not helped. Epilepsy is one condition that has been trialled with the use of CBD which has proved successful in reducing the number of seizures in patients with certain types of epilepsy. Severe epilepsy is not only life-threatening, but it can significantly impact a person’s everyday life. Some patients may experience multiple seizures a day which is exhausting, debilitating and can mean that the patient can’t lead a normal life. By reducing the number of seizures or completely stopping them, the patient may be able to hold down a job, drive and have a better quality of life. In some epileptic patients, CBD has been the solution to this. CBD has been found to manage the condition when other methods have failed.

For many, CBD has also been a way of improving mental well-being. This substance can help reduce anxiety and depression by acting on the brain’s receptors for serotonin. Low levels of serotonin are a cause of depression and it’s thought that CBD may affect how the brain’s receptors respond to serotonin. Many people use it as a stress reliever particularly if they suffer from anxiety. CBD has fewer side effects than a lot of antidepressants and maybe a safer and more effective treatment.

It’s anti-anxiety and anti-stress effects are also beneficial when it comes to sex. There have been reports of CBD enhancing sexual experiences, this may be because of its ability to help with performance anxiety and stress that many people feel before or during sexual intercourse. Although there’s not enough evidence for this yet, reports of CBD being used to improve sex have been positive with many feeling relaxed and having a more pleasurable experience. It may also reduce pain for those who have painful conditions that hinder their ability to have sex or those who experience pain during sex. Although it’s always important to get this checked out by a doctor first to establish the cause of the pain.

CBD is known to be a great pain reliever. CBD may affect the endocannabinoid system in the body which regulates a number of processes including sleep, appetite and pain. It’s thought that CBD impacts endocannabinoid receptor activity to reduce pain and inflammation. Chronic pain severely impacts all aspects of a person’s life and CBD has reduced pain for many and without side effects. However, it’s important to know that not all types of pain can be relieved by CBD as it responds differently to each person.

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County takes hard line with recent state cannabis laws, requires THC lab testing – Community Impact Newspaper

Recent laws passed this year by the state Legislature helped the cannabidiol, or CBD, market to quickly expand in south Montgomery County, with at least five CBD stores opening or announcing an opening this year as well as several existing stores adding CBD to their offerings. However, Montgomery County officials said they plan to continue prosecuting marijuana-related cases, which could affect some CBD consumers.

Local business owner Tammy Didier said she sells CBD products at her store Arolistic Naturals, which opened on FM 1488 on May 10.

“We want to educate the community here on CBD and the benefits of it and the effects of it,” Didier said.

Even though stores such as Didier’s are educating the public on possible benefits of CBD, there is confusion over what CBD actually is and what is legal in Montgomery County.

What is CBD?

Marijuana and hemp are two different plants under the same cannabis family, Didier said. The CBD customers buy from her shop is from the hemp plant, which is high in CBD and low in tetrahydrocannabinol, the psychoactive element in marijuana known as THC.

Dr. Michel Watkins, a pediatric neurologist at UT Health and Memorial Hermann-Texas Medical Center, said both CBD and THC interact with cannabinoid receptors that are located throughout the body via the endocannabinoid system—a physiological, regulatory system inside the body that is said to promote stability. But the science behind this system is still poorly understood, he said.

Didier said customers buy CBD to deal with several issues such as sleep problems, anxiety and general pain. However, the U.S. Food and Drug Administration has yet to set up regulations on the standards and practices surrounding CBD.

Walter Ybarbo said he began selling CBD in his store Texas Naturals on Ashlane Way when it became legal.

“Everything has got to be done correctly,” he said.

Ybarbo said he has lab results showing his products meet the legal requirements. The products have helped his business grow this year, he said. •“The feedback we’re getting from customers is phenomenal … we’ve had a lot of positive response,” he said.

Katharine Neil Harris, a research fellow in drug policy at Rice University’s Baker Institute for Public Policy, said there is no way to test whether CBD products come from hemp or marijuana. “So essentially those products can be bought and sold legally and without repercussions,” she said.

Montgomery County District Attorney Brett Ligon said he believes people should be wary of the CBD trend as there is little research or regulation.

“Right now, it’s kind of like the wild, wild west when it comes to CBD oil. It’s not regulated. It’s often times not tested. You don’t know where it’s being produced from,” Ligon said.

Path to legislation

Gov. Greg Abbott signed two bills into law from the 86th Texas Legislature in June that pertain to medical marijuana and hemp. House Bill 3703 allows physicians to prescribe medical marijuana for illnesses such as terminal cancer and autism, not just severe epilepsy, as the law previously said. House Bill 1325 legalized the production of hemp with a THC concentration of less than 0.3%.

State Rep. Will Metcalf, R-Conroe, said in an email HB 1325 presents a unique opportunity for Texan farmers and hemp is a viable agricultural commodity for west Texas.

Ligon spoke to the Montgomery County Commissioners Court about HB 1325 on July 9. Ligon said the problem is most police departments do not have the necessary equipment to test for the presence of THC.

Following the bill’s passage, several district attorneys, including Harris County District Attorney Kim Ogg, said they would limit how many new marijuana cases they would prosecute due to a lack of testing equipment. However, Ligon said marijuana is still illegal and his office has to uphold the law.•On July 9, a fund was established by the Montgomery County Commissioners Court to hire labs to determine the THC percentage.

Ligon said it is his duty to interpret the law to protect the residents of Montgomery County, even through difficult laws such as HB 1325.

“The role of the DA is … to make a decision based on what the community standards are and what the law is,” Ligon said.

Kara McIntyre contributed to this report.

7 Reasons Why THC Free CBD Oil Is More Beneficial Than You Think – – VENTS Magazine

According to a recent poll, nearly half of the American population believes CBD has medicinal benefits. Meanwhile, 61% would like to see CBD appear at their local drug stores.

As more people start using CBD, questions arise about the difference between THC-free CBD oil.

Understanding the benefits of 100% THC-free CBD oil can put your physical and mental pain at ease. Interested?

Keep reading to learn more about THC-free CBD oil and the seven reasons it’s more beneficial than you think.

Comparing CBD & THC

Before you discover the benefits of THC-free CBD oil, let’s talk about the difference between THC and CBD.

CBD and THC are both compounds found in the cannabis plant.

THC is the most active compound in cannabis. It creates a mind-altering “high” many of us associate with using marijuana.

CBD, on the other hand, isn’t psychoactive. That means you won’t have to worry about experiencing mind-altering effects from using zero THC CBD oil.

Both CBD and THC interact with the body’s cannabinoid receptors. These receptors cause a number of physiological effects in the body, including:

  • Inflammatory bowel disease

  • Insomnia

  • Low appetite

  • Eating disorders

  • Alzheimer’s disease

  • Muscle spasticity

  • Glaucoma

  • Pain

  • Anxiety

  • Nausea

  • Seizures

  • Depression

  • Inflammation

  • Migraines

  • Psychosis

  • Mental disorders

  • Cancer

  • Multiple sclerosis

Both THC and CBD interact with the endocannabinoid system to cause these differences.

THC-Free CBD Oil Benefits

People use CBD to treat various medical conditions and symptoms. THC-free CBD is available in different forms, including:

  • Oils

  • Tinctures

  • Edibles (brownies and gummies)

  • Capsules

  • Smoking products

  • Supplements

  • Creams and gels

Before you start using CBD, let’s cover a few of the ways zero-THC CBD oil can help your health.

  1. Natural Pain-Reliever

The human body produces two cannabinoids and two receptors for these cannabinoids: CB1 and CB2 receptors.

While CB1 is present throughout the human body, the majority are found in the brain. CB2, on the other hand, are more commonly found in the immune system. They affect pain and inflammation.

Inflammation can cause a number of issues, such as pain and headaches.

Many people take over-the-counter or prescription drugs to relieve this pain. However, THC-free CBD oil is safer and causes fewer side effects. Replacing drugs with CBD can help you reduce chronic inflammation and pain without these side effects.

  1. Down with Drug Withdrawal

If you’re a chronic smoker, consider trying CBD oil without THC. CBD can help reduce withdrawal symptoms, making it easier for you to quit.

Some smokers have even started using inhalers that contain CBD to reduce their nicotine cravings.

CBD doesn’t only benefit smokers, though. It can also help with other drug-related problems, such as opioid addiction disorders. Drug addicts with substance abuse disorders experience symptoms including anxiety, pain, insomnia, and mood-related symptoms.

By taking CBD oil THC free, addicts can relieve their symptoms and focus on their recovery.

While more research is necessary, CBD’s ability to prevent and/or reduce withdrawal symptoms can possibly help addicts get clean.

  1. Ease Epilepsy

The FDA recently approved the use of CBD for use as a safe and effective therapy for two epileptic-related conditions. In the United States, doctors can now prescribe Epidolex for Lennox-Gastaut syndrome and Dravet syndrome.

Both can cause seizures, but the types of seizures are often difficult to control with medication.

To remedy this, patients are now using THC-free CBD oil to reduce inflammation and seizures without the need for prescription medication. CBD oil is more effective in easing seizures than prescription drugs, which might cause negative side effects.

In addition to epilepsy and seizures, THC-free CBD can also help treat neurological symptoms and disorders like schizophrenia. However, more research is needed to determine the extent of CBD’s abilities to help treat certain conditions.

  1. Cancer-Fighter

Though research is still underway, CBD has shown signs that it’s also able to help prevent cancer from spreading.

The CBD compound suppresses the growth of cancer cells. At the same time, it also promotes the destruction of these cells, which keeps it from spreading.

Unlike some cancer treatments, CBD has low toxicity levels. Given this, many patients are choosing CBD in addition to their standard cancer treatments.

  1. An Answer to Anxiety

According to this study, THC-free CBD can also reduce anxiety for people with certain disorders, including:

  • Social anxiety disorder

  • General anxiety disorder

  • Post-traumatic stress disorder

  • Panic disorder

  • Obsessive-compulsive disorder

Many of the existing treatments of these conditions can cause side effects. Patients will even stop taking their medications to reduce additional side effects and symptoms.

For many patients, it’s unwise to combine cannabis and chronic anxiety. Cannabis can trigger or increase paranoia and anxiousness. CBD, on the other hand, helps reduce anxiety and other symptoms associated with related disorders.

  1. Reduce Acne & Inflammation

Inflammation causes a number of issues, including aches, pains, and even acne.

Many people have started using CBD to ease the inflammation and overworked sebaceous glands that cause acne. That inflammation builds up, causing redness and other reactions below your skin.

Acne occurs when the body overproduces sebum. Too much sebum, which is an oily substance, causes acne to occur. With CBD, you can reduce the inflammation that causes sebum to reduce your acne.

  1. Type 1 Diabetes

CBD can also ease inflammation that develops in the pancreas. When the immune system attacks the pancreas cells, causing inflammation, it leads to type 1 diabetes.

Learning more about inflammation in the pancreas can lead to a CBD-based treatment for diabetes before the condition escalates. CBD might also help protect the body, delaying the development of type 1 diabetes in at-risk patients.

Benefiting Mind & Body: 7 Reasons THC-Free CBD Oil Is So Beneficial 

Unlike THC, CBD won’t cause psychoactive effects. That means you won’t have to worry about getting high by taking a THC-free CBD oil. Instead, you can experience these seven benefits (among others) to ease your pain and inflammation-related symptoms.

Want to learn more about CBD? Check out the Miscellaneous section of the blog to discover more tips, tricks, and guides.

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5 steps to building trust and customers in your CBD business – Yahoo Finance

Denver, CO, Nov. 12, 2019 (GLOBE NEWSWIRE) — The growing cacophony of misinformation about CBD oil (cannabidiol) circulating online has consumers confused and in search of reliable sources of truth. This is a great opportunity for your brand to make its digital presence easy to find and presented in a way that is authoritative and credible. In other words, the sources you choose to cite must be trustworthy. Your website and social media accounts should curate the latest and most accurate information about CBD, in order to position your brand as a knowledgeable and trusted go-to for updates and advice.

When creating a content strategy for your communications channels, keep in mind a formula to maintain follower interest and engagement. Approximately 80% of your content should aim to educate, inform and discuss relevant issues that don’t necessarily affect your brand but are happening within the industry. The other 20% of your content can be promotional and remind people about the products and services your company provides. Nobody wants to be sold to all the time, but of course, followers expect that communications from your business will sometimes provide offers and details about the benefits that set your company apart from the competition.

And remember, there is always room to also entertain and showcase your brand’s personality, along with its authority and commitment to consistently keep it real.

Wisconsinites Use Cannabis As A Medicine, But Research And The Law Are Not Yet On Their Side – WUWM

After four decades of using strong prescription drugs to treat Crohn’s disease, a chronic digestive disorder, Patty developed an aggressive form of skin cancer.

“It’s because my body has been suppressed for so long, it can’t fight it [cancer],” the Wisconsin resident said.

Patty, who has worked at her father’s restaurant for 27 years, now struggles to handle full-time duties.

“I’m trying to get disability, but I’ve been denied once already. I don’t plan on quitting working. I just need help. I need help because I can’t do a full-time job,” Patty said.

In March 2017, a friend who lives in New Mexico, where medical marijuana is legal, mailed her Buddha Tears, a cannabis oil product containing cannabidiol (CBD), and THC, the psychotropic component of cannabis. After consuming a tiny amount of the oil each day — as well as smoking marijuana — Patty said she saw a massive improvement in her condition.

“Unfortunately, I have to smoke every day, because if I don’t, I will be in the bathroom all the time,” said Patty, who asked that her last name not be published because she is using an illegal substance.

But these days, Patty is again struggling with the symptoms.

“My connection [for CBD and marijuana] got cut off,” she said. “I’m very angry.”

While Patty and others have found success treating their medical ailments with cannabis, the drug remains illegal in Wisconsin.

And because of its status as a Schedule I drug — the most restrictive classification — there has been limited research in the United States about its effectiveness as medicine. The U.S. Food and Drug Administration has authorized one component of cannabis to treat serious and rare seizure disorders, as well as three drugs with synthetic cannabis substances; no other uses have been approved.

READ: Researching Medical Marijuana May Soon Get Easier

Although it remains illegal federally, 33 states and the District of Columbia have authorized medical use of cannabis. A bipartisan group of lawmakers has proposed legalizing it for medical use in Wisconsin, and another group of Democratic lawmakers introduced a bill in October to decriminalize possession of less than 28 grams. But Senate Majority Leader Scott Fitzgerald, R-Juneau, remains opposed.

An April poll conducted by the Marquette Law School Poll showed that 83% of registered voters polled support the use of marijuana for medical purposes with a doctor’s prescription.

“When issues receive more than 70% support from registered voters in Wisconsin, the Legislature needs to listen and act,” said Rep. David Bowen, D-Milwaukee.

Marijuana misclassified?

According to Dr. Angela Janis, director of psychiatry for University of Wisconsin-Madison’s University Health Services, Schedule I drugs, including marijuana, are considered to have no currently accepted medical use and a high potential for abuse, whereas for Schedule II drugs, there is less potential for abuse, and there is some therapeutic benefit.

Janis is intimately familiar with this distinction. In addition to her university job, Janis is chief medical officer at LeafLine Labs, a Minnesota-based medical marijuana company.

“To put this in perspective: methamphetamine is Schedule II because it’s approved for obesity. Cocaine is Schedule II because it’s approved for nasal surgery since it can constrict your blood vessels as they do surgery in your nose. So that’s the bar for what ‘medical benefit’ means,” Janis said.

According to Janis, cannabis has less abuse potential than any of those substances.

“Cannabis is not appropriately scheduled. And that’s one of the barriers, but not the only barrier, to research,” Janis said.

Janis recommends rescheduling the drug so researchers can further study its properties. Even Smart Approaches to Marijuana (SAM), which opposes marijuana legalization, is “fully supportive” of drugs containing cannabis that have been approved by the FDA, said Colton Grace, a spokesman for the group.

How marijuana works in the body

According to the National Institute on Drug Abuse, cannabinoids are substances within the cannabis plant that act on specific receptors in the human brain and body. They are the main active ingredients in the medical products derived from cannabis.

These receptors affect many essential functions, including one’s memory, thinking, concentration and coordination. Interfering with it can have profound effects — both positive and negative.

Two of the most extensively studied cannabinoids are delta-9-tetrahydrocannabinol (THC) and CBD. However, there are dozens of cannabinoids that may also have medical uses.

“Many strains of the cannabis plant can have 60, 70, 80 cannabinoids in them that all interact in different ways,” Janis said.

The National Institutes of Health reported spending $191 million on researching cannabinoids for medicinal use in 2017-18.

Some effects are already known. For example, THC can affect the central nervous system, producing benefits such as decreased vomiting and nausea, increased appetite, reduced pain and anti-inflammatory effects. CBD also acts as an anti-inflammatory, increasing immune function, reducing pain and keeping certain cells from proliferating.

Cannabinoid receptors are not in areas that control breathing, which is why there are no fatal overdoses with marijuana, Janis said. CBD actually blocks the psychotropic effects of THC, Janis said.

In addition to all those cannabinoids, the cannabis sativa plant has a lot of other chemicals. For instance, terpenes, which give each strain its particular smell, such as lemon or pine, “are thought to have a lot of effects, but we just don’t know what they actually do in the body,” Janis said.

An effective treatment for pain

In 2017, the National Academies of Sciences, Engineering and Medicine came out with one of the most comprehensive reviews of scientific research on what is known about the health effects of cannabis and cannabis-derived products. The committee considered more than 10,000 scientific abstracts. It reached nearly 100 conclusions, finding substantial evidence for just a few indications — the biggest one being pain.

The report found there is substantial evidence that cannabis is an effective treatment for chronic pain in adults, specifically nerve pain, Janis said.

The group also found conclusive evidence for cannabis treating chemotherapy-associated nausea and vomiting and MS-associated muscle spasms.

The report also showed moderate evidence that cannabis or cannabinoids are effective for improving sleep in individuals with sleep apnea, fibromyalgia, chronic pain and multiple sclerosis.

READ: In Wisconsin, Users Of Cannabis & CBD Are As Close As Main Street

It also found limited evidence for cannabis as effective for increasing appetite and decreasing weight loss associated with HIV/AIDS, relaxing muscle tightness and pain from MS, symptoms of Tourette syndrome, anxiety and post-traumatic stress disorder (PTSD).

Anecdotal evidence has also proven the effectiveness of cannabinoids for treating Rett syndrome.

Norah Lowe, 10, started feeling relief from the rare neurological disorder one year ago when she began using CBD to treat her symptoms. Rett syndrome impacts nearly every part of a child’s life, including the ability to speak, walk, eat and breathe. A distinct feature of the condition is repetitive, almost constant hand movements.

Norah, who uses a wheelchair, has experienced “increased flexibility, decreased pain and muscle cramping, increased communication, cognitive ability, reduction in seizures, better mood control, and the list goes on and on,” her father, Josh Lowe, said.

At a news conference arranged by state Rep. Melissa Sargent, D-Madison, to introduce her latest bill to legalize medical and recreational marijuana, Lowe said he is frustrated that state law prohibits Norah from trying medical marijuana, which has helped others with her condition.

A 2017 study published in the Cochrane Database of Systematic Reviews analyzed several studies, concluding that cannabis-based medicines were better than placebos for pain relief — and that these medications also improved sleep and psychological distress — it concluded that any potential benefits might be outweighed by their potential harms.

According to the Marijuana Policy Project, the most common conditions accepted by states that allow medicinal cannabis relate to the relief of the symptoms of cancer, glaucoma, HIV/AIDS and MS. Some other common indicators include Alzheimer’s disease, inflammatory bowel disease, Crohn’s, Parkinson’s disease and PTSD, according to the group, which advocates for marijuana legalization.

Additionally, the University of Michigan published a study in the February issue of Health Affairs to understand the reasons why people are using cannabis for medical purposes, and whether those purposes are evidence-based.

The authors found that 85.5% of uses of medical cannabis were for conditions for which there was substantial or conclusive evidence of their therapeutic effectiveness. Even more, they found that chronic pain is currently the most common qualifying condition reported by medical cannabis patients, used by 64.9% of such patients in 2016.

“That’s a good sign,” Janis said. “Even though a physician can write [a cannabis prescription] for a variety of things, it seems to be being used for what it’s intended for.”

Barriers to research continue

Since cannabis is a Schedule I drug, it is “very difficult to study at any institutional level” because, in order to do so, researchers need sign-offs from the U.S. Drug Enforcement Agency, which has “historically been unwilling to provide them,” said David Abernathy, vice president of data and government affairs for the Arcview Group, a firm that advises investors in the cannabis industry. 

Because of this, “Things like double-blind placebo-controlled clinical trials weren’t happening in the U.S.,” Abernathy said. But there has been a lot of research in the past decade in other countries including Israel, Canada, China and Italy, and “now we’re starting to see more research in the U.S.,” he said.

READ: New Research Challenges Arguments Made Both For & Against Medical Marijuana

The 2017 National Academies review of cannabis research agreed that the drug’s status as a Schedule I substance made it hard to study. “Researchers also often find it difficult to gain access to the quantity, quality, and type of cannabis product necessary to address specific research questions,” the review found.

Patty, the Crohn’s patient, believes that her cannabis treatment not only alleviated her Crohn’s symptoms, but she credits it with keeping her aggressive skin cancer at bay.

According to a 2018 article published in Biochemical Pharmacology, studies have shown the potential of cannabinoids to reduce of skin cancer progression. However, there is a significant lack of clinical studies promising enough to make any conclusive statements at this time.

“I haven’t had the cannabis oil since March of 2018, and once I couldn’t get it anymore, I mean I just finished my 12th surgery [for cancer],” Patty said. “So, you tell me, what do you think?”

This story was produced as part of an investigative reporting class at the University of Wisconsin-Madison School of Journalism and Mass Communication under the direction of Dee J. Hall, Wisconsin Watch’s managing editor. Wisconsin Watch’s collaborations with journalism students are funded in part by the Ira and Ineva Reilly Baldwin Wisconsin Idea Endowment at UW-Madison. The nonprofit Wisconsin Watch collaborates with Wisconsin Public Radio, Wisconsin Public Television, other news media and the UW-Madison School of Journalism and Mass Communication. All works created, published, posted or disseminated by Wisconsin Watch do not necessarily reflect the views or opinions of UW-Madison or any of its affiliates.

Best CBD oil in the UK, tried and tested – Yahoo Sports

What is CBD oil and which one should you buy? [Photo: Green Stem/ Celtic Wind]

What is CBD oil and which one should you buy? [Photo: Green Stem/ Celtic Wind]

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CBD oil has become a huge wellness trend in 2019.

The medicinal product, which you can buy off the shelves, has rapidly increased in demand over the last few years. According to the BBC there are now an estimated quarter of a million regular users in the UK alone.

The benefits of cannabis-based medicines also continue to be introduced by the NHS, with two cannabis drugs for epilepsy and multiple sclerosis being ‘approved’ for the first time in November 2019.

However, CBD oil needs no prescription, Holland & Barrett became the first high street store to stock medical cannabis oil in the UK in February 2018. It is now a common products on the high street from Superdrug to Boots.

What is CBD?

There are two main compounds in cannabis: CBD (cannabidiol) and THC (tetrahydrocannabinol). It is the THC that is the psychoactive constituent, and therefore, illegal in the UK.

CBD oil, however, is legal as it is made from a natural ingredient found in hemp plant.

“CBD is a chemical substance found in cannabis that has medical benefits. It won’t get you high, because it doesn’t contain THC (tetrahydrocannabinol), the chemical in cannabis that makes you high” explains the NHS website.

The Home Office only allows licences for oils in the UK that are cultivated from plants with approved seed types and contain a THC content of 0.2% or less.

How it helps?

Research is still being administered by multiple organisations in the UK to prove the health benefits of CBD oil. It is, however, mostly praised by users for helping insomnia, anxiety, chronic pain and period pain.

How to chose one?

Currently CBD oil is not clearly regulated, but, The World Health Organization states “CBD is generally well tolerated with a good safety profile”.

When searching for CBD oil it’s important to check it’s free from pesticides and solvents, it includes no more than 0.2% THC and that it’s from a trusted brand.

There are also varying strengths of CBD oil, the lowest being 300mg (3%) ranging to 800mg (8%). It’s suggested you start at a low dosage and gradually build up your tolerance.

We tried and tested some of the best CBD oils on the high street

CBD Oil Drops Seville Orange (5%) by Green Stem | £45

After finishing around four CBD oils over the past year, I was ecstatic when I stumbled upon Green Stem, who have created flavoured CBD oils that don’t share the usual unpleasant earthy taste. I tried the seville orange, but there’s also black cherry and peppermint. The broad-spectrum hemp blend is THC free and has been lab tested for purity. I would most definitely join customers who have already given it an overall 4.9 out of 5 rating.

Crops Oil (5%) by Celtic Wind | £29.99

Made from EU-certified hemp crops in Cooley Mountains of Ireland and produced without fungicides, pesticides or herbicides, Celtic Wind is a worthy first-time choice if you’re wanting to try a CBD oil. You’re suggested to take one pipette (0.7ml) once a day under your tongue. Other brands often allow more drops a day, so I found one drop wasn’t enough for the effects to last the entire day. However, for a CBD newbie who doesn’t want to take it numerous times a day it’s probably ideal. It also wasn’t the most pleasant tasting CBD oil (spoiler alter: CBD oil does not taste good in general, but usually the pay off is worth it).

Cannabidiol Oil (5.6%) by Dragonfly CBD | £40

Stocked at Boots, Dragonfly CBD is on the more pricer end of the spectrum. But, that is because it’s extracted from organically grown Cannabis Sativa plants using a hand-crafted extraction method. The brand are also very transparent with its production, proving organic certification, batch numbers and pesticide testing. With 5.6% CBD, it’s higher strength, and taste wise was a little less oily than others.

Super Strength CBD Oil Drops (5%) by Health Span | £28.95

I was lured in by the promise of an “easy-to-use peppermint flavoured oral drops” – and I was not disappointed. The hint of peppermint was refreshing, making it another great option for those who don’t like the usual CBD taste. The oil also held a clear consistency, showing the brands filter-clear method, which removes unwanted plant.

Raw CBD Capsules by Endoca (10mg per capsule) | from £23

Endoca is a brand that I’ve been suggested by multiple avid CBD users. It contains only full spectrum hemp oil and CBD. If you can’t stomach the not-so-pleasant tasting oils, these capsules are the solution. The only down side is that you’re confined to a fixed dosage rather than measuring it yourself using drops. However, not having to taste the oil made it so, so worth it.

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