Best CBD Vape Juice & Oil: Top 3 Brands of 2021 – EcoWatch

By Annamarie Meli

CBD has taken the world by storm thanks to its keen therapeutic properties and potential medical benefits. CBD has been praised for many things: its therapeutic uses, potential medical benefits, and anti-anxiety and relaxation properties. As CBD becomes more popular and standard, you are perhaps wondering if you can benefit from CBD.

There is a lot of misinformation about CBD out there, from claims that it can cure any disease to claims that it is actually harmful. We care about factual information here so we put together this comprehensive guide on the best CBD vape juice and oils for consumer use. All of our reviews are backed by peer-reviewed science and we take the time to vet each company that we recommend thoroughly.

Today we are going to discuss CBD vape juices and oils. Without a doubt, one of the most popular ways to consume CBD, vaping or smoking has become the top choice for consumers. What makes these products so unique is that they provide a near instant-acting dose. This can be incredibly practical for those who do not want to fuss with drops, creams or edibles. So if you are interested in learning more about the wild and wonderful world of CBD vape juice and oil, then read on.

Top CBD Vape Juice & Oil: Summary

Our peer-reviewed, non-biased system involves concise and formulated testing. To skip ahead of our in-depth discussion here are our top favorite picks:

  1. CBDfx – Best Variety & Editor’s Choice
  2. Diamond CBD – Best Value
  3. Empe USA – Great Taste

This transparent approach has provided our readers with a clear resource to make informed and educated buying decisions.

The Formula: How We Put It All Together

We take our CBD research seriously. That is why we thoroughly vet every product and brand that we recommend. Here is a list of factors we consider when choosing and ranking our brand selection.

Hemp source – Hemp source is one of the most important parts of the CBD manufacturing process. If you have poorly grown and poorly cultivated hemp, then you will have a bad product. To that end, we make sure to only pick companies that grow organic hemp according to the most up-to-date botanical and cultivation methods. We also make sure to choose companies that use organically grown, locally-sourced hemp.

Extraction process – Another important factor we consider is extraction process; i.e. how the product is made. There are 3 major types of extraction for CBD products. The first is the simplest and involves crushing the leaves and stems and removing the residual mixture. This process is simple and can be performed in your kitchen but is highly inefficient.

Solvent extraction involves running the hemp plant through a solvent mixture (most of the time it’s ethanol) then boiling away the solvent to leave the oil residue. The last common method is called supercritical CO2 extraction. With this process, supercooled liquid CO2 acts as the solvent. The CO2 is then evaporated off leaving behind the pure oil residue. Supercritical CO2 extraction is considered the gold standard when it comes to CBD production. As such, we try to find companies that use supercritical methods for their products.

Manufacturing standards – CBD is neither regulated nor approved by the FDA for medical use. As such, there are no universal federal standards for the manufacture of CBD. That being said, there are several third-party organizations that vet companies based on manufacturing standards and the quality/accuracy of their products. These agencies test company products to make sure that they are made properly and actually contain what they are advertised to contain. As such, we only choose products and companies that have readily accessible third-party lab reports ascertaining the quality of ingredients and production. Any company that does not provide this information for consumers is automatically excluded from consideration.

Type of products – CBD is a diverse molecule and can be made into many products. Some companies may specialize in a specific type of CBD product while others may make many kinds. We always make sure that companies we pick have a suitable level of diversity among their product offerings.

Extra ingredients – CBD products rarely contain just CBD and nothing else. Many contain a full spectrum of cannabinoids and other molecules such as terpenes. We make sure that any companies we choose use all-natural ingredients and do not rely on any synthetic or artificial chemicals. We also look at the type and quality of alternative ingredients

Potency – Potency refers to the overall strength of the mixture. Potency is normally measured in milligrams per milliliter (mg/ml). Most of the time a product will list the potency on the label along with the quantity and volume of the product. Potency is very important because it determines the recommended dose that you should take. More potent CBD can produce stronger effects quicker.

Brand transparency – It is important when dealing with CBD companies that the brand is transparent about their products, methods, and supply chains. So, when looking for companies, we make sure only to pick those that have reliable and transparent business practices, product labelings, and company information/policies.

Website and buying experience – Another important factor we consider is the overall experience shopping and buying on the website. It is very frustrating when you have to deal with an arduous buying or shipping process. So we take website experience and the buying process seriously when considering recommendations.

Customer reviews and testimonials – The last major factor we consider is customer reviews and testimonials. Customer reviews encompass more than just the quality of products. They also talk about how it is to interact with the company and the overall company experience. Customer reviews can also give insights in specific matters that general product descriptions cannot give. They also give a good indication of the public reputation of a company.

CBD Vape Juice & Oil: Product Info

1. CBDfx – Best Variety & Top Choice

First up on our roundup is CBDfx, which has won our admiration for their high-quality products and diverse lineup. This San Francisco-based company was founded in 2014 and has quickly become one of the best and most well-known suppliers of CBD products. Founders Ali Esmalli and Jameson Rogers were inspired to create CBDfx with the goal of providing pure, high-quality products at an affordable price.

The most distinctive feature of CBDfx is their large product lineup. Browsing through their pages, you will find oils, tinctures, vape products, edibles, gummies, creams, salves, and more. Most product types include full spectrum, broad spectrum, and isolate variants. You can pretty much find any kind of CBD product you need from CBDfx. They also have special product lines designed for specific ailments such as their Sleep and Relaxation lines. They also offer CBD products and treats for pets.

All of CBD products are made using locally sourced, organically grown hemp from California and are made using a state-of the art supercritical CO2 extraction method. This extraction method ensures a high-degree of purity and potency. As far as vaping products go, CBDfx offers vape kits complete with cartridges and vaporizer elements, as well as refills. They also offer several different flavors including watermelon, strawberry kiwi, blue raspberry, and natural flavorings. Additionally, all products are 100% vegan and do not contain artificial preservatives or flavorings.

CBDfx has made waves in the CBD community and has generally very positive customer reviews. In particular, customers appreciate the high quality products and excellent customer service. CBDfx offers free shipping on all orders above $35 but also the option to upgrade to priority mail, first class, or FedEx shipping for a small fee. As far as returns go, CBDfx offers a 30 day money-back guarantee for unused and unopened products.

Overall, CBDfx is one of the best CBD companies out there right now. They offer an extremely wide range of products and are vetted by third-party lab tests.


  • Large variety of products including tinctures, edibles, capsules, vaping kits and more
  • 100% vegan products made with supercritical CO2 extraction methods
  • Several flavor profiles including common and unconventional flavorings
  • Excellent customer reviews and testimonials
  • Free shipping on orders above $35 with options for upgraded shipping

Lab Results – All lab results for each product are included in a link on the product description page. CBDfx charters CCTL for all of their testing requirements. Their vaping product all test positive for quality and lack or impurities.

Shipping & Returns – CBDfx offers free shipping on orders above $35 to all 50 states in the US and also offers a 30-day money back guarantee for unused and unopened products. Customers must pay shipping for returns though.


  • Divers array of products
  • High quality production methods
  • Generous shipping and return policies
  • Locally source organic hemp
  • 100% vegan products


  • Slightly more expensive
  • Free shipping takes 5-8 days

Click Here To Visit The CBDfx Website.

2. Diamond CBD – Best Value

Next up on our list is Diamond CBD. This Colorado-based CBD company is one of several owned by Potnetwork Holdings which owns several other cannabis companies nationwide.

Diamond CBD, like CBDfx, has a very large product selection, including tinctures, oils, Balms, vape products, edibles, and more. Their product listing for tinctures alone is over 4 pages long. Moreover, every product has an associated lab report so you can check each product’s purity, potency, and quality.

Diamond CBD uses multiple extraction methods for their products, including solvent-based extraction, supercritical CO2 extraction, and olive oil extraction. The exact method they use for different products is different. However, the majority of products are made with supercritical CO2 extraction.

In addition to their large product lineup, Diamond CBD also has special lines for specific ailments. They have a Relax line of gummies and tinctures to promote health and combat insomnia, as well as products specifically for pain. They have products ranging in size from 500mg to 1500mg, which, while not as potent as other brands, still has good variety. All of Diamond CBD vape products are full spectrum and contain a wide blend of cannabinoids and other molecules such as terpenes.

As far as shipping goes, Diamond CBD offers free shipping on all purchases over $100. They offer a $10 flat shipping rate otherwise. One of the best aspects of Diamond CBD is how affordable their products are. Their products range between $0.05-$0.12 per mg of CBD which is on the more affordable side of the scale. They also offer a 30-day money back guarantee on all unopened and unused products.

With respect to vaping oils, CBD Diamond offers a wide selection. They offer both vape kits and vape juice refills. Their listing includes several flavorings, including strawberry, watermelon, honey, and natural flavorings.


  • Huge range of products available
  • Supercritical CO2 extraction method for the majority of its products
  • Locally sourced hemp out of Colorado and Kentucky
  • Small potency blends available for purchase
  • Extremely generous return policies

Lab results – Diamond CBD has their lab reports furnished by Green Science Labs. Their lab reports can be found at the bottom of the main page in one of the links. Each product has an associated lab report and you can search based on product name.

Shipping & Returns – Diamond CBD offers free shipping to all 50 states for purchases over $100. Otherwise, they charge a flat $10 shipping rate. They have a 30-day return policy on all unused and unopened products.


  • Wide selection of products
  • Detailed lab reports for all products
  • Very affordable prices
  • Multiple speciality lines of products
  • Large selection of flavors


  • Website design could use some work
  • Shipping rate of $10 is fairly high

Click Here To Visit The Diamond CBD Website.

3. Empe USA – Great Taste

Last on our roundup is Empe USA. This US-based CBD company offers 100% organic CBD products and includes a decent range of product types. Empe USA makes all of their products using locally sourced hemp and does not include any synthetic or artificial ingredients.

Empe offers a decent range of products, including oils, tinctures, gummies, creams, salves, and more. Their vape products are all isolate blends and contain no other molecules. Empe USA also features lab reports for all of their products. You can find lab reports at the bottom of the page and search for specific products listings.

Empe USA offers CBD vape juice concentrations of 350mg. Their products are on the more expensive side of the spectrum with $0.12 per mg of CBD. However, the company frequently offers discounts so you can usually get something for a lower price than what is listed.

The vast majority of reviewers claim that Empe USA’s products helped them achieve relaxation and reduced pain. There were also several reviews claiming that their skin products helped manage conditions like dry and cracked skin.

AS far as their vaping products go, Empe USA offers a wide selection of vaping juice refills, entire vaping kits, and solo disposable cartridges. Most of their flavors are modeled after the taste of famous cannabis strains such as Blue Dream or Gorilla OG.

Empe offers free shipping on all orders over $100. Otherwise, they charge a flat $5.95 rate, which is fairly low, all things considered. They also offer a standard 30-day return policy for all unused and unopened items. Customers must handle shipping costs for returns though.


  • Excellent quality products
  • Wide selection of CBD products
  • Good natural flavors
  • Wide selection of vaping products
  • Free shipping for orders over $100

Lab Results – All Empe US lab reports are furnished by Steep Hill labs. You can browse lab reports by clicking on the link at the bottom of the page.

Shipping & Returns – Empe US offers free shipping on all orders over $100 to all 50 states. They charge a flat $5.95 shipping rate for all orders under $100. They also offer a standard 30-day return policy which, while not amazing, is fairly standard for CBD companies.


  • Good selection of products
  • Large selection of vaping products
  • Free shipping on orders over $100
  • Great flavors modeled after traditional cannabis strains
  • Lab reports for all products


  • Website is slightly confusing to navigate
  • Extraction method is not specified on official website
  • Return policy is not amazing

Click Here To Visit The EMPE USA Website.

Where Does CBD Come From?

CBD comes from the cannabis plant, however, there is a bit more nuance to it than just that. Cannabis can be divided into two main types of plants called marijuana and hemp. Marijuana typically refers to cannabis plants that contain more than 0.3% THC per mass while hemp refers to cannabis plants that have less than 0.3% THC by mass. Most CBD oils are made from hemp and so contain a very low if not negligible amount of THC.

CBD oil can also be divided into types based on the ingredients. Isolates are the most pure form and only contain CBD suspended in some matrix, normally vegetable glycerin or glycol. Broad spectrum blends include a larger variety of cannabinoids such as CBG, CBC, and CBN. Full spectrum blends contain a diverse cannabinoid profile including THC, as well as other molecules such as terpenes, vitamins, and fatty acids.

What Are CBD Vape Products?

CBD can be vaporized and inhaled. To that end, many companies offer CBD vaping products. These products normally involve a vape with disposable or refillable cartridges. The vape apparatus vaporizes the CBD contained in the cartridge, which is then inhaled. It is the same principle behind e-cigarettes and THC vape products.

CBD vape products can be found in isolate, broad spectrum, or full spectrum varieties. Each kind of variety is suited for a specific purpose. Most CBD vaping products are normally broad or full spectrum and usually contain THC, however some do not. Full spectrum vaping products also contain other molecules such as terpenes.

Vaporization is normally considered a potent way to ingest CBD and so it is not for everyone. Because the vapor is inhaled, the molecule enters the bloodstream much quicker, so vaping produces a fast and relatively intense feeling.

How Does CBD Work?

CBD has become an interesting object of study by scientists because of its potential therapeutic and medicinal properties. CBD has been shown to:

  • Reduce anxiety
  • Reduce inflammation
  • Reduce nociceptive and neuropathic pain
  • Manage neuropathy
  • Has neuroprotective properties
  • Anti-tumor benefits

Out of all these effects, the pain reducing and anti-inflammatory properties of CBD are the most well-established. CBD has been shown to have anti-inflammatory properties and has also been shown to be as effective as several traditional methods of pain management. There is also some evidence that CBD might have anti-tumor properties, although there is still no consensus on that matter. CBD has been noted as particularly effective in managing cancer and cancer-treatment related symptoms such as pain, loss of appetite, and anxiety.

To be clear, CBD is not medicine and is not generally approved by the FDA for medical use. CBD is not intended to serve as a substitute or replacement for any approved medical treatment and CBD is not known to cure any diseases.

In fact, there are only 2 FDA-approved medicines that contain CBD as their active ingredient, both of which are meant to treat certain forms of epilepsy. Since CBD is not approved for medical use, you should always talk to your doctor first before using a CBD product.

Endocannabinoid System

The exact mechanism of action of CBD is still a matter of scientific investigation, though there is a growing consensus that CBD works on the body’s endocannabinoid system. The endocannabinoid is a large network of cannabinoid receptors throughout the body’s brain and nervous tissue. Research has shown that the endocannabinoid system is involved in mediating several homeostatic processes in the body.

As such, there is a growing belief in the medical community that several seemingly disparate chronic conditions might be explained by an imbalance in the body’s endocannabinoid system. Conditions such as fibromyalgia, IBS, and some auto-immune conditions might be related to the endocannabinoid system. CBD has become a target of interest to medical researchers in virtue of its effects on the system.

The endocannabinoid system contains two types of receptors, dubbed CB1 and CB2. CB1 receptors are located primarily in the brain while CB2 receptors are located primarily in the central and peripheral nervous system. CBD is a partial agonist of both receptors, so while it does interact with the receptors, it does not fully fit into the „lock-and-key” mechanism. The exact nature of CBD’s interaction with CB1 and CB2 receptors is still a matter of investigation.

THC also interacts with the endocannabinoid receptors but in a different way. Thus CBD is not associated with the psychoactive effects of THC. You will not get „high” from CBD, although many report a sense of general relaxation and calm after taking CBD.

Dosage and Side Effects

CBD is not regulated or approved by the FDA so there are no accepted standards as to what the acceptable dosage of CBD is. Experiments involving CBD range from very small doses to fairly high doses, though few experiments focus specifically on finding the proper dosage per unit of dobby weight.

However, most experts recommend that you start with a dosage of 1 mg of CBD per 10 lbs. Of body weight. So for example, if you weigh 150 lbs, then a good recommended dose to start with would be 15mg. You should always start with a smaller does and slowly increase the dosage by 1-2mg per week until you achieve the desired effects. It is generally not recommended to exceed more than 100mg of CBD per day, although this depends on your specific situation.

CBD has been shown to be non-toxic, even in extremely high doses. The LD50 of CBD in humans has not been determined but animal studies show that it is likely extremely high and CBD does not produce lasting negative effects even at very high doses. As such, it is virtually impossible that you could overdose on CBD. It is also not associated with a „hangover” or withdrawal effects as it is non-addictive and non-habit forming.

Side Effects

CBD does have a handful of side effects, though most of them are mild and tend to go away once you get used to taking the product. The most common reported side effects of CBD are:

  • Dry mouth
  • Fatigue/lethargy
  • Indigestion
  • Changes in appetite
  • Upset stomach

The most commonly reported side effect is fatigue and tiredness. The other side effects tend to decrease as you body acclimates to taking the supplement. However, the specific side effects you experience may be heavily dependent on your individual bodily constitution. Some people just react differently to the molecule.


CBD has quickly become one of the most popular therapeutic methods for managing a diverse range of conditions. CBD used to be fairly expensive but increased customer demand and competition between businesses has resulted in a large amount of affordable CBD products for the average consumer. As CBD becomes more popular, we can expect even more company and a wider range of CBD products. This is good news for you as you will have more choices than ever.

Based on our round up, CBDfx is the top CBD provider. They offer a wide range of high-quality products with a solid range of concentrations/potencies. CBDfs also uses high-quality organic CBD for its products and uses a sophisticated supercritical CO2 extraction method. In that sense, CBDfx is one of the best CBD providers on the market right now and any enthusiast can find something to love from them.

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